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Filers›Hedge Fund›Foresite Capital Management VI LLC
DOSSIER · 13F-HR · Q4 2025

Foresite Capital Management VI LLC

Foresite VI's hedge fund based in Greenwich, CT — $331M in tracked AUM across 12 positions as of Q4 2025.

FV
Foresite VI·Greenwich, CT·Hedge Fund
CIK 0002013341 · last filed Dec 31, 2025
Total AUM
$331M
▲ 12.9%
vs prior
Holdings
12
—
positions
Whale Score
62
62
tracked
Activity
—
no data
changes this Q
Top sector
Financials
18% weight
concentration
AI Analysis · Q4 2025 · Q4 2025

1. Portfolio Overview

The SEC 13F filing for Foresite Capital Management VI LLC reveals a period of significant consolidation and portfolio reduction for the quarter ending September 30, 2025. The firm executed a drastic reduction in assets under management (AUM), with the total portfolio value plummeting by 70.4% from $177.88M to $52.61M. This de-risking was achieved through a massive reduction in the number of holdings, which shrank from a much broader basket to just **5 posit...

Quarter at a glance — Q4 2025

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q4 2025.

#HoldingValueSharesWeight
01
CGON
CG Oncology, Inc.
$92M2.2M27.9%
02
RAPT
RAPT Therapeutics, Inc.
$53M1.6M16.0%
03
ALMS
ALUMIS INC.
$41M4.2M12.5%
04
CNTA
Centessa Pharmaceuticals plc
$34M1.4M10.3%
05
VSTM
Verastem, Inc.
$24M3.1M7.3%
06
DNLI
Denali Therapeutics Inc.
$17M1.0M5.0%
07
NTRA
Natera, Inc.
$15M67K4.7%
08
AGIO
AGIOS PHARMACEUTICALS, INC.
$14M530K4.4%
09
KYMR
Kymera Therapeutics, Inc.
$11M146K3.4%
10
N0731H103
Atai Beckley N.V.
$11M2.8M3.4%

Filing history

Filing history loading…
AI Agent · grounded in Foresite
haiku-4-5 · 12 positions indexed
Sector mix
  • Financials18%
  • Cons. Disc.6%
  • Communications50%
  • Industrials5%
  • Energy12%
  • Other9%
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