DOSSIER · 13F-HR · Q4 2025

Iron Triangle Partners LP

$875M in tracked AUM across 27 positions as of Q4 2025.

IT
CIK 0001779763 · last filed Dec 31, 2025
Total AUM
$875M
as of Q4 2025
Holdings
27
positions
Whale Score
57
57
tracked
Activity
no data
changes this Q
AI Analysis · Q4 2025

Iron Triangle Partners runs a tightly concentrated, 27-position, $874.7 million healthcare book, and this quarter it turned over more than half of it while staying entirely within the sector. Sixteen of the 27 holdings are brand new, including a $53.5 million stake in Intuitive Surgical, a $40.1 million position in Boston Scientific and a $39.9 million stake in Waters Corp, while the fund exited Dexcom ($57.2 million), AbbVie ($46.4 million) and Medtronic ($43.2 million) entirely. The through-line is a rotation from payors and diagnostics-adjacent names toward life-science tools and CDMO exposure: Charles River Labs (CRL) — already the top holding — grew from 6.0% to 8.7% of the book on a $33.8 million buy, and new positions in Waters, Bruker (BRKR) and Bio-Techne (TECH) reinforce the same lab-instrumentation theme. Meanwhile CVS Health, the largest single holding a quarter ago at 8.6% of the portfolio, was cut nearly in half by share count (-45.8%, -$25.8 million) and now ranks well down the list. Iron Triangle isn't diversifying out of healthcare — it's actively trading within it.

Iron Triangle Partners LP holds just 27 positions across an $874.7 million book, and the quarter ended December 31, 2025 shows extraordinary churn for a portfolio this concentrated: 16 new positions and 14 full exits against a base of 27 holdings — more than half the book turned over in a single quarter. And yet every dollar of it stayed inside healthcare and life sciences; the sector allocation is effectively unchanged even as the individual names underneath it were almost entirely replaced.

Building out the tools and diagnostics sleeve
Analysis generated by 13F Insight from SEC Form 13F filing data · Q4 2025. Methodology

Quarter at a glance — Q4 2025

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q4 2025.

#HoldingValueSharesWeight
01
CRL
CHARLES RIV LABS INTL INC
$76M380K8.7%
02
ISRG
INTUITIVE SURGICAL INC
$53M94K6.1%
03
RGEN
REPLIGEN CORP
$53M320K6.0%
04
G50871105
JAZZ PHARMACEUTICALS PLC
$50M292K5.7%
05
VCYT
VERACYTE INC
$41M980K4.7%
06
BSX
BOSTON SCIENTIFIC CORP
$40M421K4.6%
07
WAT
WATERS CORP
$40M105K4.6%
08
BKD
BROOKDALE SR LIVING INC
$38M3.5M4.3%
09
LLY
ELI LILLY & CO
$38M35K4.3%
10
BRKR
BRUKER CORP
$37M794K4.3%

Filing history

2025Q4Dec 31
$875M 24.4%
27 positionsView →
2025Q3Sep 30
$703M 8.0%
25 positionsView →
2025Q2Jun 30
$651M 39.0%
27 positionsLocked
2025Q1Mar 31
$468M 48.4%
21 positionsLocked
2024Q4Dec 31
$908M 25.9%
23 positionsLocked
2024Q3Sep 30
$722M 26.6%
25 positionsLocked
2024Q2Jun 30
$984M 0.8%
26 positionsLocked
2024Q1Mar 31
$976M 26.3%
29 positionsLocked
2023Q4Dec 31
$773M 13.0%
26 positionsLocked
2023Q3Sep 30
$684M 8.5%
23 positionsLocked
2023Q2Jun 30
$748M 7.9%
23 positionsLocked
2023Q1Mar 31
$693M 24.3%
27 positionsLocked
Showing 12 of 25