DOSSIER · 13F-HR · Q4 2025

Politan Capital Management LP

$841M in tracked AUM across 3 positions as of Q4 2025.

PC
CIK 0001885245 · last filed Dec 31, 2025
Total AUM
$841M
as of Q4 2025
Holdings
3
positions
Whale Score
66
66
tracked
Activity
no data
changes this Q
AI Analysis · Q4 2025

Portfolio Overview

Politan Capital Management LP’s 13F filing for the period ending September 30, 2025, reveals a dramatic transformation in the fund's structure and risk profile. The total portfolio value plummeted by 80.2%, decreasing from $1.39 billion in the previous quarter to $276.3 million. This drastic reduction in assets under management (AUM) is likely attributable to significant client redemptions rather than pure market depreciation, given the magnitude of the drop w...

Concurrent with the decline in capital, the fund executed a massive simplification of its portfolio, reducing the number of holdings from approximately 20 (inferred from the activity summary) down to just 9. The fund has shifted from a diversified multi-hundred-million-dollar strategy to a highly concentrated "conviction" portfolio. The turnover was exceptionally high, with the fund exiting 11 positions while initiating only 1 new position. This indicates a strategic pivot toward capital preservation or a preparation for a wind-down, moving away from a broad activist-style engagement model to a focused holding pattern.

Key Holdings

Quarter at a glance — Q4 2025

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q4 2025.

#HoldingValueSharesWeight
01
MASI
MASIMO CORP
$597M4.6M71.0%
02
AZTA
AZENTA INC
$154M4.6M18.3%
03
CNC
CENTENE CORP DEL
$90M2.2M10.7%

Filing history

2025Q4Dec 31
$841M 204.2%
3 positionsView →
2025Q3Sep 30
$276M 80.2%
9 positionsView →
2025Q2Jun 30
$1.4B 168.2%
19 positionsLocked
2025Q1Mar 31
$519M 66.4%
2 positionsLocked
2024Q4Dec 31
$1.5B 12.9%
4 positionsLocked
2024Q3Sep 30
$1.8B 7.9%
4 positionsLocked
2024Q2Jun 30
$1.6B 14.7%
3 positionsLocked
2024Q1Mar 31
$1.9B 9.8%
3 positionsLocked
2023Q4Dec 31
$1.8B 18.6%
3 positionsLocked
2023Q3Sep 30
$1.5B 12.5%
3 positionsLocked
2023Q2Jun 30
$1.7B 1.9%
3 positionsLocked
2023Q1Mar 31
$1.7B 3.2%
2 positionsLocked
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