DOSSIER · 13F-HR · Q1 2026

Sarissa Capital Management LP

$158M in tracked AUM across 9 positions as of Q1 2026.

SC
CIK 0001577524 · last filed Mar 31, 2026
Total AUM
$158M
as of Q1 2026
Holdings
9
positions
Whale Score
69
69
tracked
Activity
no data
changes this Q
AI Analysis · Q1 2026

Portfolio Overview

Sarissa Capital Management LP’s 13F filing for the period ending September 30, 2025, reveals a highly specialized and concentrated investment portfolio. With a total value of approximately $149.50 million, the fund decreased in size by 3.2% compared to the previous quarter's $154.39 million. The portfolio is exceptionally narrow, comprising only five holdings, which indicates a conviction-based strategy rather than a broad market index approach. The fund maintains a clear...

Key Holdings

The portfolio is dominated by four core positions, each representing a significant double-digit weighting, while the fifth position serves as a minor allocation.

Quarter at a glance — Q1 2026

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q1 2026.

#HoldingValueSharesWeight
01
INVA
INNOVIVA INC
$50M2.1M31.5%
02
IRWD
IRONWOOD PHARMACEUTICALS INC
$32M9.2M20.5%
03
AMRN
AMARIN CORP PLC
$24M1.7M15.3%
04
NBIX
NEUROCRINE BIOSCIENCES INC
$15M117K9.7%
05
CYTK
CYTOKINETICS INC
$15M229K9.6%
06
LNTH
LANTHEUS HLDGS INC
$13M167K8.0%
07
G1110E107
BIOHAVEN LTD
$5M563K3.0%
08
REGN
REGENERON PHARMACEUTICALS
$3M4K2.1%
09
VOR
VOR BIOPHARMA INC
$453K25K0.3%

Filing history

2026Q1Mar 31
$158M 29.3%
9 positionsView →
2025Q4Dec 31
$223M 49.1%
9 positionsView →
2025Q3Sep 30
$149M 3.2%
5 positionsView →
2025Q2Jun 30
$154M 15.7%
7 positionsLocked
2025Q1Mar 31
$133M 58.7%
4 positionsLocked
2024Q4Dec 31
$323M 19.8%
8 positionsLocked
2024Q3Sep 30
$402M 32.1%
10 positionsLocked
2024Q2Jun 30
$592M 3.6%
10 positionsLocked
2024Q1Mar 31
$572M 11.9%
10 positionsLocked
2023Q4Dec 31
$649M 12.6%
9 positionsLocked
2023Q3Sep 30
$742M 26.1%
11 positionsLocked
2023Q2Jun 30
$1.0B 28.5%
11 positionsLocked
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