DOSSIER · 13F-HR · Q1 2026

Sarissa Capital Management LP

Sarissa's family office based in San Francisco, CA $158M in tracked AUM across 9 positions as of Q1 2026.

S
Sarissa·San Francisco, CA·Family Office
CIK 0001577524 · last filed Mar 31, 2026
Total AUM
$158M
3.6%
vs prior
Holdings
9
positions
Whale Score
71
71
strong
Activity
no data
changes this Q
Top sector
Tech
19% weight
concentration
AI Analysis · Q1 2026 · Q1 2026

Portfolio Overview

Sarissa Capital Management LP’s 13F filing for the period ending September 30, 2025, reveals a highly specialized and concentrated investment portfolio. With a total value of approximately $149.50 million, the fund decreased in size by 3.2% compared to the previous quarter's $154.39 million. The portfolio is exceptionally narrow, comprising only five holdings, which indicates a conviction-based strategy rather than a broad market index approach. The fund maintains a clear...

Quarter at a glance — Q1 2026

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q1 2026.

#HoldingValueSharesWeight
01
INVA
INNOVIVA INC
$50M2.1M31.5%
02
IRWD
IRONWOOD PHARMACEUTICALS INC
$32M9.2M20.5%
03
AMRN
AMARIN CORP PLC
$24M1.7M15.3%
04
NBIX
NEUROCRINE BIOSCIENCES INC
$15M117K9.7%
05
CYTK
CYTOKINETICS INC
$15M229K9.6%
06
LNTH
LANTHEUS HLDGS INC
$13M167K8.0%
07
G1110E107
BIOHAVEN LTD
$5M563K3.0%
08
REGN
REGENERON PHARMACEUTICALS
$3M4K2.1%
09
VOR
VOR BIOPHARMA INC
$453,11825K0.3%

Filing history

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