13F Insight
DOSSIER · 13F Holders · Q4 2025

PROTAGONIST THERAPEUTICS

21 institutions still hold PROTAGONIST THERAPEUTICS as of Q4 2025. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 74366E106·21 13F holders·last filed Dec 31, 2025
Market cap
—
13F value held
$148M
visible holders
Holders
21
filers reporting
Concentration
60.57%
MARSHALL WACE, LLP #1
top holder share
AI Holders Summary · Q4 2025

21 institutions reported PROTAGONIST THERAPEUTICS in Q4 2025. MARSHALL WACE, LLP leads at 60.6% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
MARSHALL WACE, LLP
CIK 0001318757
$90M1.0M0.08%Q4 202502
JENNISON ASSOCIATES LLC
CIK 0000053417
$29M331K0.02%Q4 202503
Alyeska Investment Group, L.P.
CIK 0001453072
$17M200K0.05%Q4 202504
Louisiana State Employees Retirement System
CIK 0001537191
$2M27K0.04%Q4 202505
KEYSTONE INVESTORS PTE LTD
CIK 0001926253
$2M26K0.21%Q4 202506
VIRGINIA RETIREMENT SYSTEMS ET Al
CIK 0001005354
$2M25K0.01%Q4 202507
Glenmede Investment Management, LP
CIK 0001644465
$1M18K0.01%Q3 202508
COMERICA BANK
CIK 0000901541
$1M13K0.00%Q4 202509
FORA Capital, LLC
CIK 0001742435
$788K9K0.10%Q4 202510
Horizon Investments, LLC
CIK 0001560717
$652K7K0.01%Q4 202511
Inspire Investing, LLC
CIK 0001670139
$531K5K0.03%Q1 202612
Orion Portfolio Solutions, LLC
CIK 0001802647
$326K7K0.00%Q1 202513
PNC FINANCIAL SERVICES GROUP, INC.
CIK 0000713676
$229K3K0.00%Q4 202514
AlphaQuest LLC
CIK 0001883897
$141K2K0.01%Q4 202515
ASSETMARK, INC
CIK 0001344551
$25K2850.00%Q4 202516
SageView Advisory Group, LLC
CIK 0001914558
$9K1060.00%Q4 202517
Annis Gardner Whiting Capital Advisors, LLC
CIK 0001998414
$7K760.00%Q4 202518
Elyxium Wealth, LLC
CIK 0002043538
$2K220.00%Q4 202519
Physician Wealth Advisors, Inc.
CIK 0001795173
$2K210.00%Q4 202520
ORG Partners LLC
CIK 0001979372
$2K190.00%Q4 2025
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