DEFINIUM THERAPEUTICS INC COM SHS

The top of the register blends passive and active conviction. BlackRock leads at about $160 million, but the next two are dedicated growth and healthcare investors: Driehaus Capital Management at roughly $112 million and Avoro Capital Advisors at $94.5 million. Avoro in particular is a biotech-specialist fund, so its $94.5M position reads as a fundamental bet rather than index exposure.

For DFTX readers, the institutional story is one of real depth and conviction: an index anchor in BlackRock alongside two specialist managers with nine-figure positions. That combination of breadth (238 holders) and concentrated specialist interest is exactly the profile that draws further institutional attention.