13F Insight
DOSSIER · 13F Holders · Q2 2026
DFTX

DEFINIUM THERAPEUTICS INC COM SHS

360 institutions still hold DEFINIUM THERAPEUTICS INC COM SHS as of Q2 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 24477V105·360 13F holders·last filed Jun 30, 2026
Market cap
—
13F value held
$3.4B
visible holders
Holders
360
filers reporting
Concentration
15.49%
BlackRock, Inc. #1
top holder share
AI Holders Summary · Q2 2026

Definium Therapeutics (DFTX) carries one of the deepest institutional books in this set — 238 holders and about $1.39B in combined 13F value as of Q1 2026. BlackRock leads at roughly $160M, followed by growth specialist Driehaus Capital ($112M) and healthcare-dedicated Avoro Capital ($94.5M). The mix of an index giant with two conviction biotech investors marks genuine institutional depth.

The top of the register blends passive and active conviction. BlackRock leads at about $160 million, but the next two are dedicated growth and healthcare investors: Driehaus Capital Management at roughly $112 million and Avoro Capital Advisors at $94.5 million. Avoro in particular is a biotech-specialist fund, so its $94.5M position reads as a fundamental bet rather than index exposure.

For DFTX readers, the institutional story is one of real depth and conviction: an index anchor in BlackRock alongside two specialist managers with nine-figure positions. That combination of breadth (238 holders) and concentrated specialist interest is exactly the profile that draws further institutional attention.

Analysis generated by 13F Insight from SEC Form 13F filing data · Q2 2026. Methodology

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
BlackRock, Inc.
CIK 0002012383
$528M11.2M0.01%Q2 202602
Avoro Capital Advisors LLC
CIK 0001633313
$338M7.2M3.04%Q2 202603
DRIEHAUS CAPITAL MANAGEMENT LLC
CIK 0000938206
$322M6.8M1.87%Q2 202604
Jupiter Topco LLC
CIK 0002146052
$264M5.6M0.11%Q2 202605
Capital World Investors
CIK 0001422849
$252M5.4M0.03%Q2 202606
FMR LLC
CIK 0000315066
$224M4.8M0.01%Q2 202607
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$171M3.6M0.01%Q2 202608
STATE STREET CORP
CIK 0000093751
$144M3.1M0.00%Q2 202609
Capital International Investors
CIK 0001562230
$139M3.0M0.03%Q2 202610
Octagon Capital Advisors LP
CIK 0001839435
$139M3.0M12.47%Q2 202611
WELLINGTON MANAGEMENT GROUP LLP
CIK 0000902219
$139M2.9M0.02%Q2 202612
Deep Track Capital, LP
CIK 0001856083
$129M2.8M1.88%Q2 202613
Commodore Capital LP
CIK 0001831942
$94M2.0M5.60%Q2 202614
SUSQUEHANNA INTERNATIONAL GROUP, LLP
CIK 0001446194· Market maker
$89M1.9M0.01%Q2 202615
GOLDMAN SACHS GROUP INC
CIK 0000886982
$85M1.8M0.01%Q2 202616
Vanguard Portfolio Management
CIK 0002100121· Index
$78M1.6M0.00%Q2 202617
RA CAPITAL MANAGEMENT, L.P.
CIK 0001346824
$71M1.5M0.61%Q2 202618
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$70M1.5M0.00%Q2 202619
JANUS HENDERSON GROUP PLC
CIK 0001274173
$67M3.6M0.03%Q1 202620
Siren, L.L.C.
CIK 0002005245
$67M1.4M1.35%Q2 2026
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Insiders at DEFINIUM THERAPEUTICS INC COM SHS
Roberts Brandi →Wiley Matthew T. →Sullivan Mark →Barrow Robert →Karlin Daniel →Adsett Roger →