DOSSIER · 13F Holders · Q1 2026Defensive growthQuality
DFTX

DEFINIUM THERAPEUTICS INC COM SHS

238 institutions still hold DEFINIUM THERAPEUTICS INC COM SHS as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 24477V105·238 13F holders·last filed Mar 31, 2026
Market cap
3.1%
vs prior quarter
13F value held
$954M
73.0% inst. owned
of float
Holders
238
+44 QoQ
filers reporting
Activity
+86 / −30
+904 added · −889 reduced
this quarter
Concentration
16.79%
BlackRock, Inc. #1
top holder share
AI Holders Summary · Q1 2026

Definium Therapeutics (DFTX) carries one of the deepest institutional books in this set — 238 holders and about $1.39B in combined 13F value as of Q1 2026. BlackRock leads at roughly $160M, followed by growth specialist Driehaus Capital ($112M) and healthcare-dedicated Avoro Capital ($94.5M). The mix of an index giant with two conviction biotech investors marks genuine institutional depth.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
BlackRock, Inc.
CIK 0002012383
$160M8.5M0.00%Q1 2026
02
DRIEHAUS CAPITAL MANAGEMENT LLC
CIK 0000938206
$112M5.9M0.82%Q1 2026
03
Avoro Capital Advisors LLC
CIK 0001633313
$95M5.0M0.93%Q1 2026
04
JANUS HENDERSON GROUP PLC
CIK 0001274173
$67M3.6M0.03%Q1 2026
05
Deep Track Capital, LP
CIK 0001856083
$57M3.0M0.93%Q1 2026
06
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$47M2.5M0.00%Q1 2026
07
STATE STREET CORP
CIK 0000093751
$47M2.5M0.00%Q1 2026
08
Octagon Capital Advisors LP
CIK 0001839435
$46M2.4M5.10%Q1 2026
09
MARSHALL WACE, LLP
CIK 0001318757
$40M3.0M0.04%Q4 2025
10
Commodore Capital LP
CIK 0001831942
$38M2.0M2.19%Q1 2026
11
FMR LLC
CIK 0000315066
$34M1.8M0.00%Q1 2026
12
GOLDMAN SACHS GROUP INC
CIK 0000886982
$32M1.7M0.00%Q1 2026
13
WELLINGTON MANAGEMENT GROUP LLP
CIK 0000902219
$25M1.3M0.00%Q1 2026
14
Candriam S.C.A.
CIK 0001537014
$24M1.3M0.13%Q1 2026
15
BALYASNY ASSET MANAGEMENT L.P.
CIK 0001218710
$24M1.3M0.03%Q1 2026
16
TWO SIGMA INVESTMENTS, LP
CIK 0001179392
$23M1.2M0.02%Q1 2026
17
ADAGE CAPITAL PARTNERS GP, L.L.C.
CIK 0001165408
$22M1.1M0.03%Q1 2026
18
SUSQUEHANNA INTERNATIONAL GROUP, LLP
CIK 0001446194· Market maker
$22M1.1M0.00%Q1 2026
19
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$21M1.1M0.00%Q1 2026
20
Holocene Advisors, LP
CIK 0001700574
$21M1.1M0.05%Q1 2026
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