13F Insight
DOSSIER · 13F Holders · Q4 2025BellwetherCompounder
HRTX

HERON THERAPEUTICS INC

176 institutions still hold HERON THERAPEUTICS INC as of Q4 2025. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 427746102·176 13F holders·last filed Dec 31, 2025
Market cap
—
▼ 7.2%
vs prior quarter
13F value held
$134M
47.0% inst. owned
of float
Holders
176
-124 QoQ
filers reporting
Activity
+11 / −6
+870 added · −862 reduced
this quarter
Concentration
29.11%
Rubric Capital Management LP #1
top holder share
AI Holders Summary · Q4 2025

176 institutions reported HRTX in Q4 2025. Rubric Capital Management LP leads at 29.1% of the visible book. -124 net institutions QoQ — distribution reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
Rubric Capital Management LP
CIK 0001687509
$39M30.0M0.47%Q4 202502
Clearline Capital LP
CIK 0001600136
$16M12.2M0.78%Q4 202503
BlackRock, Inc.
CIK 0002012383
$8M10.1M0.00%Q1 202604
ORBIMED ADVISORS LLC
CIK 0001055951
$8M9.8M0.16%Q1 202605
Velan Capital Investment Management LP
CIK 0001848809
$7M8.8M4.39%Q1 202606
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$6M7.8M0.00%Q1 202607
MILLENNIUM MANAGEMENT LLC
CIK 0001273087
$6M7.6M0.00%Q1 202608
Tejara Capital Ltd
CIK 0001879713
$5M6.3M1.67%Q1 202609
TANG CAPITAL MANAGEMENT LLC
CIK 0001232621
$5M6.3M0.25%Q1 202610
PALISADE CAPITAL MANAGEMENT, LP
CIK 0001009006
$5M6.1M0.16%Q1 202611
D. E. Shaw & Co., Inc.
CIK 0001009207
$4M3.0M0.00%Q4 202512
Focus Partners Wealth
CIK 0001542153
$4M148K0.00%Q4 202513
Congress Park Capital LLC
CIK 0001730945
$3M4.0M0.99%Q1 202614
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$3M4.0M0.00%Q1 202615
STATE STREET CORP
CIK 0000093751
$3M3.8M0.00%Q1 202616
JW Asset Management, LLC
CIK 0001549738
$3M3.8M1.23%Q1 202617
CITADEL ADVISORS LLC
CIK 0001423053
$3M2.1M0.00%Q4 202518
Pale Fire Capital SE
CIK 0001922318
$2M2.7M0.19%Q1 202619
NEW YORK STATE COMMON RETIREMENT FUND
CIK 0000810265
$2M2.6M0.00%Q1 202620
Caption Management, LLC
CIK 0001706766
$2M2.4M0.01%Q1 2026
Page 1 of 9
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