AI Holders Summary · Q1 2026

92 institutions reported KPTI in Q1 2026. Ikarian Capital, LLC leads at 11.0% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(3 on this page)

#HolderValueShares% port.Quarter

Ikarian Capital, LLC

CIK 0001778253

$14M2.6M1.16%Q1 2026 02

BlackRock, Inc.

CIK 0002012383

$14M1.4M0.00%Q2 2026 03

Commodore Capital LP

CIK 0001831942

$11M1.9M0.63%Q1 2026 04

RA CAPITAL MANAGEMENT, L.P.

CIK 0001346824

$11M1.9M0.11%Q1 2026 05

ADAGE CAPITAL PARTNERS GP, L.L.C.

CIK 0001165408

$10M1.8M0.02%Q1 2026 06

T. Rowe Price Investment Management, Inc.

CIK 0001897612

$9M1.5M0.01%Q1 2026 07

SUSQUEHANNA INTERNATIONAL GROUP, LLP

CIK 0001446194· Market maker

$7M1.3M0.00%Q1 2026 08

Opaleye Management Inc.

CIK 0001595855

$7M930K0.90%Q4 2025 09

Caption Management, LLC

CIK 0001706766

$7M1.2M0.04%Q1 2026 10

Avidity Partners Management LP

CIK 0001791827

$6M927K0.69%Q1 2026 11

GOLDMAN SACHS GROUP INC

CIK 0000886982

$5M948K0.00%Q1 2026 12

Catalio Capital Management, LP

CIK 0001958125

$5M898K1.04%Q1 2026 13

BOOTHBAY FUND MANAGEMENT, LLC

CIK 0001549230

$4M750K0.05%Q1 2026 14

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$4M740K0.00%Q1 2026 15

JANE STREET GROUP, LLC

CIK 0001595888· Market maker

$3M594K0.00%Q1 2026 16

STATE STREET CORP

CIK 0000093751

$3M326K0.00%Q2 2026 17

MILLENNIUM MANAGEMENT LLC

CIK 0001273087

$3M512K0.00%Q1 2026 18

Affinity Asset Advisors, LLC

CIK 0001773195

$3M500K0.14%Q1 2026 19

Soleus Capital Management, L.P.

CIK 0001802630

$2M440K0.10%Q1 2026 20

ADAR1 Capital Management, LLC

CIK 0001940272

$2M342K0.11%Q1 2026

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