13F Insight
DOSSIER · 13F Holders · Q4 2025Healthcare · Pharmaceutical PreparationsMost-boughtAI cap-ex
NUVL

NUVALENT INC

275 institutions still hold NUVALENT INC as of Q4 2025. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 670703107·Pharmaceutical Preparations·275 13F holders·last filed Dec 31, 2025
Market cap
—
▼ 4.1%
vs prior quarter
13F value held
$6.4B
78.0% inst. owned
of float
Holders
275
-119 QoQ
filers reporting
Activity
+25 / −89
+831 added · −745 reduced
this quarter
Concentration
27.04%
DEERFIELD MANAGEMENT COMPANY, L.P. #1
top holder share
AI Holders Summary · Q4 2025

275 institutions reported NUVL in Q4 2025. DEERFIELD MANAGEMENT COMPANY, L.P. leads at 27.0% of the visible book. -119 net institutions QoQ — distribution reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
DEERFIELD MANAGEMENT COMPANY, L.P.
CIK 0001009258
$1.7B17.2M22.16%Q4 202502
FMR LLC
CIK 0000315066
$950M9.3M0.05%Q1 202603
Paradigm Biocapital Advisors LP
CIK 0001855655
$545M5.3M11.15%Q1 202604
BlackRock, Inc.
CIK 0002012383
$494M4.8M0.01%Q1 202605
JPMORGAN CHASE & CO
CIK 0000019617
$299M3.1M0.02%Q1 202606
RA CAPITAL MANAGEMENT, L.P.
CIK 0001346824
$260M2.5M2.75%Q1 202607
Vanguard Portfolio Management
CIK 0002100121
$256M2.5M0.01%Q1 202608
WELLINGTON MANAGEMENT GROUP LLP
CIK 0000902219
$253M2.5M0.05%Q1 202609
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$249M2.4M0.01%Q1 202610
STATE STREET CORP
CIK 0000093751
$209M2.0M0.01%Q1 202611
Polar Capital Holdings Plc
CIK 0001837309
$188M1.8M0.67%Q1 202612
PERCEPTIVE ADVISORS LLC
CIK 0001224962
$162M1.6M3.16%Q1 202613
Deep Track Capital, LP
CIK 0001856083
$141M1.4M2.30%Q1 202614
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$133M1.3M0.01%Q1 202615
JANUS HENDERSON GROUP PLC
CIK 0001274173
$127M1.2M0.06%Q1 202616
Bellevue Group AG
CIK 0001674546
$104M1.0M1.98%Q4 202517
Commodore Capital LP
CIK 0001831942
$85M834K4.94%Q1 202618
ALLIANCEBERNSTEIN L.P.
CIK 0001109448
$79M784K0.03%Q1 202619
ADAGE CAPITAL PARTNERS GP, L.L.C.
CIK 0001165408
$77M749K0.12%Q1 202620
BRAIDWELL LP
CIK 0001920938
$72M700K2.39%Q1 2026
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