DOSSIER · 13F-HR · Q2 2026

Blue Water Life Science Advisors, LP

$159M in tracked AUM across 9 positions as of Q2 2026.

BW
CIK 0001789778 · last filed Jun 30, 2026
Total AUM
$159M
as of Q2 2026
Holdings
9
positions
Whale Score
71
71
strong
Activity
no data
changes this Q
AI Analysis · Q2 2026
Comprehensive Analysis of Blue Water Life Science Advisors, LP (SEC 13F)
Portfolio Overview

Blue Water Life Science Advisors, LP manages a highly concentrated, specialized portfolio with a total value of $86.83 million as of the reporting period ending September 30, 2025. The firm employs a high-conviction investment strategy, holding only six positions, which indicates a preference for selectivity over broad diversification. The portfolio experienced a significant contraction of 31.3% in ...

Key Holdings

The portfolio is dominated by Adaptive Biotechnologies (ADPT), which constitutes the largest single holding at $32.09 million, representing 36.96% of the total assets. This suggests a strong conviction in the company’s immunosequencing platform. The second-largest position, Guardant Health (GH), accounts for 29.19% of the portfolio ($25.34 million). Together, these two positions comprise over 66% of the fund's invested capital, indicating a "barbell" strategy where the firm's performance is heavily correlated with the success of its top two liquid biopsy and genomic profiling names. The remaining holdings—Personalis, CareDx, Tempus AI, and Quanterix—are smaller positions ranging from 6% to 13% of the portfolio, providing exposure to adjacent areas of precision medicine and diagnostics.

Sector Allocation

The sector allocation demonstrates an extreme concentration in the Healthcare sector, which commands $70.05 million or approximately 80.7% of the portfolio. This aligns with the firm's name ("Life Science Advisors") and suggests a thematic investment approach focused on biotechnology, diagnostics, and life sciences tools. The Technology sector accounts for $5.84 million (6.73%), entirely represented by the new position in Tempus AI. A small portion of the portfolio (12.59%) is classified as "Unknown," corresponding to Personalis, Inc. (likely due to ticker classification nuances), though this company also operates within the healthcare and diagnostics space. Effectively, the portfolio is a pure-play on the healthcare/life sciences ecosystem with negligible exposure to other sectors.

Analysis generated by 13F Insight from SEC Form 13F filing data · Q2 2026. Methodology

Quarter at a glance — Q2 2026

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q2 2026.

#HoldingValueSharesWeight
01
CDNA
CAREDX INC
$34M1.2M21.4%
02
TXG
10X GENOMICS INC
$25M642K15.5%
03
PSNL
PERSONALIS INC
$22M1.7M14.1%
04
ADPT
ADAPTIVE BIOTECHNOLOGIES COR
$22M1.0M13.6%
05
GH
GUARDANT HEALTH INC
$17M115K10.8%
06
QTRX
QUANTERIX CORP
$15M3.5M9.5%
07
NTRA
NATERA INC
$9M34K5.9%
08
BLLN
BILLIONTOONE INC
$8M70K5.3%
09
TEM
TEMPUS AI INC
$6M105K3.8%

Filing history

2026Q2Jun 30
$159M 27.3%
9 positionsView →
2026Q1Mar 31
$125M 21.7%
10 positionsView →
2025Q4Dec 31
$159M 83.5%
9 positionsView →
2025Q3Sep 30
$87M 31.3%
6 positionsView →
2025Q2Jun 30
$126M 76.9%
8 positionsLocked
2025Q1Mar 31
$71M 36.7%
6 positionsLocked
2024Q4Dec 31
$113M 0.7%
9 positionsLocked
2024Q3Sep 30
$114M 10.6%
8 positionsLocked
2024Q2Jun 30
$103M 3.3%
8 positionsLocked
2024Q1Mar 31
$106M 6.9%
8 positionsLocked
2023Q4Dec 31
$114M 7.8%
9 positionsLocked
2023Q3Sep 30
$106M 28.5%
7 positionsLocked
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