AI Holders Summary · Q4 2025

144 institutions reported QTRX in Q4 2025. Portolan Capital Management, LLC leads at 21.4% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(5 on this page)

#HolderValueShares% port.Quarter

Portolan Capital Management, LLC

CIK 0001350290

$29M4.5M1.54%Q4 2025 02

BlackRock, Inc.

CIK 0002012383

$16M3.6M0.00%Q2 2026 03

Blue Water Life Science Advisors, LP

CIK 0001789778

$15M3.5M9.45%Q2 2026 04

First Eagle Investment Management, LLC

CIK 0001325447

$12M2.8M0.02%Q2 2026 05

Invenomic Capital Management LP

CIK 0001769456

$10M1.5M0.45%Q4 2025 06

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$8M1.8M0.00%Q2 2026 07

Lionhunter Capital Management, LLC

CIK 0002137268

$6M1.5M2.92%Q2 2026 08

Kent Lake PR LLC

CIK 0002037231

$5M1.0M2.75%Q3 2025 09

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$5M1.1M0.00%Q2 2026 10

AMERIPRISE FINANCIAL INC

CIK 0000820027

$4M987K0.00%Q2 2026 11

MARSHALL WACE, LLP

CIK 0001318757

$4M974K0.00%Q2 2026 12

STATE STREET CORP

CIK 0000093751

$4M932K0.00%Q2 2026 13

Empire Financial Management Company, LLC

CIK 0001971875

$3M736K0.59%Q1 2026 14

Tikvah Management LLC

CIK 0001606477

$2M572K0.75%Q2 2026 15

MILLENNIUM MANAGEMENT LLC

CIK 0001273087

$2M689K0.00%Q1 2026 16

Vanguard Portfolio Management

CIK 0002100121· Index

$2M490K0.00%Q2 2026 17

Topline Capital Management, LLC

CIK 0001792549

$2M563K0.33%Q1 2026 18

MORGAN STANLEY

CIK 0000895421

$2M448K0.00%Q2 2026 19

DIMENSIONAL FUND ADVISORS LP

CIK 0000354204· Quasi-passive

$2M398K0.00%Q2 2026 20

NORTHERN TRUST CORP

CIK 0000073124· Index

$1M337K0.00%Q2 2026

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