DOSSIER · 13F-HR · Q1 2026

Prosight Management, LP

$610M in tracked AUM across 46 positions as of Q1 2026.

PM
CIK 0001617201 · last filed Mar 31, 2026
Total AUM
$610M
as of Q1 2026
Holdings
46
positions
Whale Score
68
68
tracked
Activity
no data
changes this Q
AI Analysis · Q1 2026
Comprehensive Analysis of Prosight Management, LP 13F Filing

Report Period: Q3 2025 (Ending September 30, 2025)

1. Portfolio Overview

Prosight Management, LP manages a concentrated portfolio valued at approximately $365.72 million, spread across 34 holdings. The firm experienced a decrease in total portfolio value of -10.8% compared to the previous quarter ($410.06M). This decline is attributable to a combination of market depreciation and active capital reallocation, evid...

The portfolio is highly concentrated, with the top 10 positions accounting for approximately 61.8% of total assets. The largest single holding, Galapagos NV, constitutes 10.89% of the portfolio, indicating a high-conviction approach where the firm is willing to take meaningful idiosyncratic risk on specific names. The turnover for the quarter was significant, with 33 out of 34 positions seeing changes in share count (either increases, decreases, or complete exits), signaling an active management style focused on constant re-evaluation of the risk/reward profile of its holdings.

2. Key Holdings

Quarter at a glance — Q1 2026

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q1 2026.

#HoldingValueSharesWeight
01
NKTR
NEKTAR THERAPEUTICS
$53M735K8.7%
02
BSX
BOSTON SCIENTIFIC CORP
$50M796K8.2%
03
JANX
JANUX THERAPEUTICS INC
$49M3.5M8.1%
04
PRCT
PROCEPT BIOROBOTICS CORP
$49M1.9M8.0%
05
GLPG
GALAPAGOS NV
$47M1.6M7.6%
06
WGS
GENEDX HOLDINGS CORP
$34M523K5.5%
07
STTK
SHATTUCK LABS INC
$32M5.0M5.3%
08
H0036K147
ADC THERAPEUTICS SA
$31M8.3M5.1%
09
KURA
KURA ONCOLOGY INC
$27M3.4M4.5%
10
ALNY
ALNYLAM PHARMACEUTICALS INC
$25M76K4.1%

Filing history

2026Q1Mar 31
$610M 26.0%
46 positionsView →
2025Q4Dec 31
$484M 32.3%
38 positionsView →
2025Q3Sep 30
$366M 10.8%
34 positionsView →
2025Q2Jun 30
$410M 53.1%
39 positionsLocked
2025Q1Mar 31
$268M 26.0%
32 positionsLocked
2024Q4Dec 31
$362M 11.0%
36 positionsLocked
2024Q3Sep 30
$406M 21.5%
47 positionsLocked
2024Q2Jun 30
$335M 6.9%
46 positionsLocked
2024Q1Mar 31
$359M 44.3%
44 positionsLocked
2023Q4Dec 31
$249M 21.1%
35 positionsLocked
2023Q3Sep 30
$316M 7.6%
41 positionsLocked
2023Q2Jun 30
$342M 62.0%
37 positionsLocked
Showing 12 of 31