DOSSIER · 13F Holders · Q1 2026
NKTR

NEKTAR THERAPEUTICS

221 institutions still hold NEKTAR THERAPEUTICS as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 640268306·221 13F holders·last filed Mar 31, 2026
Market cap
13F value held
$1.2B
visible holders
Holders
221
filers reporting
Concentration
25.27%
FMR LLC #1
top holder share
AI Holders Summary · Q1 2026

Nektar Therapeutics (NKTR, CUSIP 640268306) entered Q1 2026 with $1.7B of institutional 13F value across 200 institutional accounts — a holder profile appropriate for a clinical-stage biopharmaceutical company whose proprietary polymer-conjugation and drug-delivery platform underpins a pipeline spanning oncology, immunology, and pain, with its lead assets reaching late-stage clinical development that generates institutional conviction at the fundamental biotech manager tier. The defining Q1 signal: FMR LLC added $305M — a massive conviction build at a size representing approximately 18% of the total reported institutional value in a single quarter — alongside 6 new positions among an already-concentrated 200-holder universe. For smart-money trackers, NKTR's Q1 filing is one of the highest-conviction-position events in this batch, with FMR's $305M add signaling fundamental confidence in the company's pipeline readouts and potential partnership or acquisition opportunities at the large-cap-biotech valuation tier. The stock's institutional footprint reflects both generalist healthcare-fundamental managers and specialized biotech-conviction players.

Q1 2026 context: NKTR-214 (bempegaldesleukin) is a differentiated IL-2 pathway agonist designed to activate CD122-preferential signaling (favoring effector T cells over regulatory T cells) for immuno-oncology combination therapy. BMS (Bristol Myers Squibb) partnership provides Nektar with milestone and royalty participation. NKTR-358 is a similar IL-2 approach for autoimmune diseases — Lilly partnership. The readout catalyst is clinical data in I/O combinations and autoimmune indications.

FMR +$305M is the dominant story: FMR is building a position that is ~18% of total institutional value in a single quarter. This is extreme conviction — FMR's analysts are treating NKTR as a multi-bagger or acquisition-candidate probability rather than a diversified biotech sleeve position.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
FMR LLC
CIK 0000315066
$310M4.3M0.02%Q1 2026
02
Two Seas Capital LP
CIK 0001823138
$141M2.0M1.97%Q1 2026
03
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$86M1.2M0.00%Q1 2026
04
TWO SIGMA INVESTMENTS, LP
CIK 0001179392
$67M931K0.05%Q1 2026
05
BVF INC/IL
CIK 0001056807
$66M1.6M2.22%Q4 2025
06
SUSQUEHANNA INTERNATIONAL GROUP, LLP
CIK 0001446194· Market maker
$65M903K0.01%Q1 2026
07
Prosight Management, LP
CIK 0001617201
$53M735K8.67%Q1 2026
08
BlackRock, Inc.
CIK 0002012383
$50M693K0.00%Q1 2026
09
MORGAN STANLEY
CIK 0000895421
$47M659K0.00%Q1 2026
10
ARMISTICE CAPITAL, LLC
CIK 0001601086
$42M578K0.74%Q1 2026
11
Invesco Ltd.
CIK 0000914208
$41M567K0.00%Q1 2026
12
Sofinnova Investments, Inc.
CIK 0001631134
$37M510K1.39%Q1 2026
13
Woodline Partners LP
CIK 0001784547
$30M415K0.11%Q1 2026
14
LORD, ABBETT & CO. LLC
CIK 0000728100
$29M405K0.10%Q1 2026
15
MILLENNIUM MANAGEMENT LLC
CIK 0001273087
$29M404K0.01%Q1 2026
16
Bronte Capital Management Pty Ltd.
CIK 0001471085
$29M401K2.86%Q1 2026
17
EMERALD ADVISERS, LLC
CIK 0001015083
$28M395K0.90%Q1 2026
18
Qube Research & Technologies Ltd
CIK 0001729829
$28M391K0.03%Q1 2026
19
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$25M347K0.00%Q1 2026
20
UBS Group AG
CIK 0001610520
$23M320K0.00%Q1 2026
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Insiders at NEKTAR THERAPEUTICS
Robin Howard WZalevsky JonathanWilson Mark AndrewWhitfield Roy ABrainard DianaAjer Jeffrey RobertChess RobertGreer R Scott