AI Holders Summary · Q2 2026

687 institutions reported INSM in Q2 2026. FMR LLC leads at 11.1% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(3 on this page)

#HolderValueShares% port.Quarter

FMR LLC

CIK 0000315066

$1.7B16.1M0.07%Q2 2026 02

BlackRock, Inc.

CIK 0002012383

$1.7B15.8M0.03%Q2 2026 03

BAKER BROS. ADVISORS LP

CIK 0001263508

$1.1B6.6M6.72%Q4 2025 04

Vanguard Portfolio Management

CIK 0002100121· Index

$1.1B10.4M0.05%Q2 2026 05

JPMORGAN CHASE & CO

CIK 0000019617

$1.1B10.4M0.06%Q2 2026 06

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$1.0B9.8M0.02%Q2 2026 07

Capital International Investors

CIK 0001562230

$878M8.2M0.18%Q2 2026 08

D. E. Shaw & Co., Inc.

CIK 0001009207

$760M4.4M0.42%Q4 2025 09

Darwin Global Management, Ltd.

CIK 0001839209

$674M6.4M17.91%Q2 2026 10

AMERIPRISE FINANCIAL INC

CIK 0000820027

$659M6.2M0.13%Q2 2026 11

Orbis Allan Gray Ltd

CIK 0001663865

$648M6.1M2.23%Q2 2026 12

STATE STREET CORP

CIK 0000093751

$645M6.1M0.02%Q2 2026 13

Artisan Partners Limited Partnership

CIK 0001466153

$580M5.4M0.92%Q2 2026 14

RTW INVESTMENTS, LP

CIK 0001493215

$516M4.8M4.41%Q2 2026 15

PRICE T ROWE ASSOCIATES INC /MD/

CIK 0000080255

$506M3.1M0.06%Q1 2026 16

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$449M4.2M0.02%Q2 2026 17

NORGES BANK

CIK 0001374170· Sovereign

$360M3.4M0.04%Q2 2026 18

CITADEL ADVISORS LLC

CIK 0001423053

$340M3.2M0.04%Q2 2026 19

NWI MANAGEMENT LP

CIK 0001103887

$332M2.0M9.43%Q1 2026 20

MILLENNIUM MANAGEMENT LLC

CIK 0001273087

$312M2.9M0.11%Q2 2026

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