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Filers›Asset Manager›BAKER BROS. ADVISORS LP
DOSSIER · 13F-HR · Q4 2025

BAKER BROS. ADVISORS LP

BAKER BROS.'s asset manager based in Boston, MA — $17.1B in tracked AUM across 86 positions as of Q4 2025.

BB
BAKER BROS.·Boston, MA·Asset Manager
CIK 0001263508 · last filed Dec 31, 2025
Total AUM
$17.1B
▲ 9.8%
vs prior
Holdings
86
—
positions
Whale Score
75
75
strong
Activity
—
no data
changes this Q
Top sector
Tech
35% weight
concentration
AI Analysis · Q4 2025 · Q4 2025
Comprehensive Analysis of Baker Bros. Advisors LP SEC 13F Filing (Q3 2025)
Portfolio Overview

Baker Bros. Advisors LP manages a concentrated portfolio valued at approximately $10.18 billion as of September 30, 2025. The fund experienced a slight contraction of -1.3% in total value compared to the previous quarter ($10.31B), amidst a period of significant portfolio turnover. The fund currently holds 67 positions, indicating a focused investment strategy rather than broad diversi...

Quarter at a glance — Q4 2025

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q4 2025.

#HoldingValueSharesWeight
01
INCY
Incyte Corporation
$3.0B30.7M17.8%
02
ONC
BeOne Medicines Ltd.
$2.7B8.8M15.7%
03
MDGL
Madrigal Pharmaceuticals, Inc.
$1.2B2.1M7.3%
04
INSM
Insmed Incorporated
$1.1B6.6M6.7%
05
ACAD
ACADIA Pharmaceuticals Inc.
$1.1B42.9M6.7%
06
CELC
Celcuity Inc.
$790M7.9M4.6%
07
RVMD
Revolution Medicines, Inc.
$753M9.5M4.4%
08
KYMR
Kymera Therapeutics, Inc.
$674M8.7M3.9%
09
SMMT
Summit Therapeutics Inc.
$636M36.4M3.7%
10
RYTM
Rhythm Pharmaceuticals, Inc.
$600M5.6M3.5%

Filing history

Filing history loading…
AI Agent · grounded in BAKER
haiku-4-5 · 86 positions indexed
Sector mix
  • Tech35%
  • Financials9%
  • Cons. Disc.11%
  • Industrials29%
  • Energy18%
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