AI Holders Summary · Q4 2025

301 institutions reported RYTM in Q4 2025. BAKER BROS. ADVISORS LP leads at 13.4% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(3 on this page)

#HolderValueShares% port.Quarter

BAKER BROS. ADVISORS LP

CIK 0001263508

$600M5.6M3.51%Q4 2025 02

RA CAPITAL MANAGEMENT, L.P.

CIK 0001346824

$580M6.7M6.14%Q1 2026 03

BlackRock, Inc.

CIK 0002012383

$542M6.2M0.01%Q1 2026 04

PRIMECAP MANAGEMENT CO/CA/

CIK 0000763212

$297M3.4M0.23%Q1 2026 05

Vanguard Portfolio Management

CIK 0002100121· Index

$264M3.0M0.01%Q1 2026 06

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$258M3.0M0.01%Q1 2026 07

PERCEPTIVE ADVISORS LLC

CIK 0001224962

$206M2.4M4.03%Q1 2026 08

STATE STREET CORP

CIK 0000093751

$198M2.3M0.01%Q1 2026 09

GOLDMAN SACHS GROUP INC

CIK 0000886982

$171M2.0M0.02%Q1 2026 10

WESTFIELD CAPITAL MANAGEMENT CO LP

CIK 0001177719

$168M1.9M0.70%Q1 2026 11

FMR LLC

CIK 0000315066

$147M1.7M0.01%Q1 2026 12

PRICE T ROWE ASSOCIATES INC /MD/

CIK 0000080255

$144M1.7M0.02%Q1 2026 13

Polar Capital Holdings Plc

CIK 0001837309

$141M1.6M0.50%Q1 2026 14

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$123M1.4M0.01%Q1 2026 15

JPMORGAN CHASE & CO

CIK 0000019617

$120M1.6M0.01%Q1 2026 16

FEDERATED HERMES, INC.

CIK 0001056288

$112M1.3M0.18%Q1 2026 17

Checkpoint Capital L.P.

CIK 0001977548

$107M1.2M38.30%Q1 2026 18

JENNISON ASSOCIATES LLC

CIK 0000053417

$98M919K0.06%Q4 2025 19

ALLIANCEBERNSTEIN L.P.

CIK 0001109448

$97M910K0.03%Q1 2026 20

Capital Research Global Investors

CIK 0001422848

$97M1.1M0.02%Q1 2026

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