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Filers›Hedge Fund›Siren, L.L.C.
DOSSIER · 13F-HR · Q1 2026

Siren, L.L.C.

Siren, L.L.C.'s hedge fund based in Stamford, CT — $3.6B in tracked AUM across 102 positions as of Q1 2026.

SL
Siren, L.L.C.·Stamford, CT·Hedge Fund
CIK 0002005245 · last filed Mar 31, 2026
Total AUM
$3.6B
▲ 12.7%
vs prior
Holdings
102
—
positions
Whale Score
63
63
tracked
Activity
—
no data
changes this Q
Top sector
Tech
15% weight
concentration
AI Analysis · Q1 2026 · Q1 2026
Comprehensive Analysis of SEC 13F Filing: Siren, L.L.C.
1. Portfolio Overview

Siren, L.L.C. manages a concentrated portfolio valued at approximately $1.79 billion as of September 30, 2025, representing a decrease of 7.5% from the previous quarter's $1.93 billion. The portfolio consists of 81 holdings, indicating a focused investment strategy rather than broad diversification.

The fund demonstrates a distinct "barbell" approach in terms of asset allocation. A massive portion of the portfol...

Quarter at a glance — Q1 2026

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q1 2026.

#HoldingValueSharesWeight
01
SRRK
Scholar Rock Holding Corp
$532M10.8M14.8%
02
KYMR
Kymera Therapeutics Inc
$265M3.2M7.4%
03
ERAS
Erasca Inc
$182M11.2M5.0%
04
EWTX
Edgewise Therapeutics Inc
$140M4.4M3.9%
05
ONC
BeOne Medicines AG
$138M465K3.8%
06
TNGX
Tango Therapeutics Inc
$118M5.7M3.3%
07
BCAX
Bicara Therapeutics Inc
$115M5.8M3.2%
08
RVMD
Revolution Medicines Inc
$108M1.1M3.0%
09
ARWR
Arrowhead Pharmaceuticals Inc
$101M1.6M2.8%
10
MANE
Veradermics Inc
$95M1.5M2.6%

Filing history

Filing history loading…
AI Agent · grounded in Siren,
haiku-4-5 · 102 positions indexed
Sector mix
  • Tech15%
  • Financials9%
  • Health Care8%
  • Cons. Disc.44%
  • Industrials20%
  • Energy6%
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