13F Insight
DOSSIER · 13F Holders · Q1 2026Most-boughtAI cap-ex
EWTX

EDGEWISE THERAPEUTICS INC

230 institutions still hold EDGEWISE THERAPEUTICS INC as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 28036F105·230 13F holders·last filed Mar 31, 2026
Market cap
—
▲ 1.1%
vs prior quarter
13F value held
$2.8B
50.0% inst. owned
of float
Holders
230
-106 QoQ
filers reporting
Activity
+38 / −56
+792 added · −824 reduced
this quarter
Concentration
17.31%
ORBIMED ADVISORS LLC #1
top holder share
AI Holders Summary · Q1 2026

230 institutions reported EWTX in Q1 2026. ORBIMED ADVISORS LLC leads at 17.3% of the visible book. -106 net institutions QoQ — distribution reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
ORBIMED ADVISORS LLC
CIK 0001055951
$489M15.5M9.73%Q1 202602
RA CAPITAL MANAGEMENT, L.P.
CIK 0001346824
$328M10.4M3.48%Q1 202603
Paradigm Biocapital Advisors LP
CIK 0001855655
$232M7.4M4.74%Q1 202604
BlackRock, Inc.
CIK 0002012383
$204M6.5M0.00%Q1 202605
JANUS HENDERSON GROUP PLC
CIK 0001274173
$186M5.9M0.09%Q1 202606
BAKER BROS. ADVISORS LP
CIK 0001263508
$163M6.6M0.96%Q4 202507
DRIEHAUS CAPITAL MANAGEMENT LLC
CIK 0000938206
$141M4.5M1.04%Q1 202608
Siren, L.L.C.
CIK 0002005245
$140M4.4M3.87%Q1 202609
PERCEPTIVE ADVISORS LLC
CIK 0001224962
$139M4.4M2.72%Q1 202610
Novo Holdings A/S
CIK 0001388325
$133M5.3M10.31%Q4 202511
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$119M3.8M0.00%Q1 202612
Cormorant Asset Management, LP
CIK 0001583977
$103M3.3M5.16%Q1 202613
BRAIDWELL LP
CIK 0001920938
$74M2.3M2.47%Q1 202614
MORGAN STANLEY
CIK 0000895421
$71M2.2M0.00%Q1 202615
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$56M1.8M0.00%Q1 202616
STATE STREET CORP
CIK 0000093751
$54M1.7M0.00%Q1 202617
MPM BioImpact LLC
CIK 0001687078
$52M1.7M4.04%Q1 202618
Integral Health Asset Management, LLC
CIK 0001773206
$50M1.6M2.41%Q1 202619
Soleus Capital Management, L.P.
CIK 0001802630
$46M1.4M1.85%Q1 202620
ALLIANCEBERNSTEIN L.P.
CIK 0001109448
$43M1.7M0.01%Q1 2026
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