AI Holders Summary · Q4 2025

289 institutions reported CELC in Q4 2025. BAKER BROS. ADVISORS LP leads at 18.6% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(3 on this page)

#HolderValueShares% port.Quarter

BAKER BROS. ADVISORS LP

CIK 0001263508

$790M7.9M4.62%Q4 2025 02

PERCEPTIVE ADVISORS LLC

CIK 0001224962

$357M3.1M6.97%Q1 2026 03

Avoro Capital Advisors LLC

CIK 0001633313

$356M3.4M3.19%Q2 2026 04

RTW INVESTMENTS, LP

CIK 0001493215

$346M3.3M2.95%Q2 2026 05

BlackRock, Inc.

CIK 0002012383

$316M3.0M0.00%Q2 2026 06

STATE STREET CORP

CIK 0000093751

$205M2.0M0.01%Q2 2026 07

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$196M1.9M0.00%Q2 2026 08

NEA Management Company, LLC

CIK 0001512848

$179M1.7M11.27%Q2 2026 09

Soleus Capital Management, L.P.

CIK 0001802630

$178M1.7M6.14%Q2 2026 10

DEERFIELD MANAGEMENT COMPANY, L.P.

CIK 0001009258

$171M1.7M2.18%Q4 2025 11

BANK OF AMERICA CORP /DE/

CIK 0000070858

$154M1.5M0.01%Q2 2026 12

PRICE T ROWE ASSOCIATES INC /MD/

CIK 0000080255

$146M1.3M0.02%Q1 2026 13

MORGAN STANLEY

CIK 0000895421

$140M1.3M0.01%Q2 2026 14

TORONTO DOMINION BANK

CIK 0000947263

$132M1.3M0.15%Q2 2026 15

TANG CAPITAL MANAGEMENT LLC

CIK 0001232621

$120M1.1M6.09%Q1 2026 16

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$116M1.1M0.01%Q2 2026 17

WELLINGTON MANAGEMENT GROUP LLP

CIK 0000902219

$95M907K0.02%Q2 2026 18

GOLDMAN SACHS GROUP INC

CIK 0000886982

$91M870K0.01%Q2 2026 19

SUSQUEHANNA INTERNATIONAL GROUP, LLP

CIK 0001446194· Market maker

$90M856K0.01%Q2 2026 20

Hood River Capital Management LLC

CIK 0001578177

$66M628K0.48%Q2 2026

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