DOSSIER · 13F-HR · Q4 2025

DEERFIELD MANAGEMENT COMPANY, L.P.

DEERFIELD COMPANY, L.P.'s family office based in San Francisco, CA $7.8B in tracked AUM across 150 positions as of Q4 2025.

DC
DEERFIELD COMPANY, L.P.·San Francisco, CA·Family Office
CIK 0001009258 · last filed Dec 31, 2025
Total AUM
$7.8B
4.4%
vs prior
Holdings
150
positions
Whale Score
64
64
tracked
Activity
no data
changes this Q
Top sector
Tech
29% weight
concentration
AI Analysis · Q4 2025 · Q4 2025

1. Portfolio Overview

Deerfield Management Company, L.P. reported a significant contraction in portfolio value for the quarter ending September 30, 2025, with total assets under management (AUM) decreasing by 29.6%, falling from $5.51 billion to $3.88 billion. This reduction is not solely attributable to market performance but indicates substantial active portfolio restructuring. The firm currently holds 92 positions, suggesting a focused strategy that balances high-conviction core holdings...

Quarter at a glance — Q4 2025

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q4 2025.

#HoldingValueSharesWeight
01
NUVL
NUVALENT INC
$1.7B17.2M22.2%
02
BKD 3.5 10/15/29
BROOKDALE SR LIVING INC
$427M306.9M5.5%
03
COGT
COGENT BIOSCIENCES INC
$321M9.0M4.1%
04
PRAX
PRAXIS PRECISION MEDICINES I
$266M903K3.4%
05
CNC
CENTENE CORP DEL
$265M6.4M3.4%
06
VTRS
VIATRIS INC
$252M20.2M3.2%
07
RVMD
REVOLUTION MEDICINES INC
$231M2.9M2.9%
08
UTHR
UNITED THERAPEUTICS CORP DEL
$208M426K2.7%
09
VERA
VERA THERAPEUTICS INC
$206M4.1M2.6%
10
MIRM 4 05/01/29
MIRUM PHARMACEUTICALS INC
$181M70.0M2.3%

Filing history

Filing history loading…