13F Insight
DOSSIER · 13F Holders · Q1 2026Mega-capCrowded
PRAX

PRAXIS PRECISION MEDICINES I

304 institutions still hold PRAXIS PRECISION MEDICINES I as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 74006W207·304 13F holders·last filed Mar 31, 2026
Market cap
—
▼ 1.7%
vs prior quarter
13F value held
$7.6B
65.0% inst. owned
of float
Holders
304
-79 QoQ
filers reporting
Activity
+66 / −43
+884 added · −876 reduced
this quarter
Concentration
14.63%
JANUS HENDERSON GROUP PLC #1
top holder share
AI Holders Summary · Q1 2026

304 institutions reported PRAX in Q1 2026. JANUS HENDERSON GROUP PLC leads at 14.6% of the visible book. -79 net institutions QoQ — distribution reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
JANUS HENDERSON GROUP PLC
CIK 0001274173
$1.1B3.5M0.53%Q1 202602
Orbis Allan Gray Ltd
CIK 0001663865
$797M2.5M3.36%Q1 202603
BlackRock, Inc.
CIK 0002012383
$749M2.3M0.01%Q1 202604
FMR LLC
CIK 0000315066
$696M2.2M0.04%Q1 202605
PERCEPTIVE ADVISORS LLC
CIK 0001224962
$656M2.0M12.82%Q1 202606
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$394M1.2M0.01%Q1 202607
BAKER BROS. ADVISORS LP
CIK 0001263508
$332M1.1M1.94%Q4 202508
DRIEHAUS CAPITAL MANAGEMENT LLC
CIK 0000938206
$306M949K2.25%Q1 202609
Cormorant Asset Management, LP
CIK 0001583977
$285M886K14.33%Q1 202610
STATE STREET CORP
CIK 0000093751
$285M884K0.01%Q1 202611
MORGAN STANLEY
CIK 0000895421
$269M833K0.02%Q1 202612
DEERFIELD MANAGEMENT COMPANY, L.P.
CIK 0001009258
$266M903K3.40%Q4 202513
ADAGE CAPITAL PARTNERS GP, L.L.C.
CIK 0001165408
$263M816K0.41%Q1 202614
Vanguard Portfolio Management
CIK 0002100121
$244M757K0.01%Q1 202615
GOLDMAN SACHS GROUP INC
CIK 0000886982
$229M711K0.03%Q1 202616
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$210M651K0.01%Q1 202617
BANK OF AMERICA CORP /DE/
CIK 0000070858
$172M535K0.01%Q1 202618
RA CAPITAL MANAGEMENT, L.P.
CIK 0001346824
$120M374K1.28%Q1 202619
Hood River Capital Management LLC
CIK 0001578177
$116M359K1.16%Q1 202620
Vivo Capital, LLC
CIK 0001674712
$109M339K9.08%Q1 2026
Page 1 of 16
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