DOSSIER · 13F-HR · Q2 2026

Darwin Global Management, Ltd.

$3.8B in tracked AUM across 5 positions as of Q2 2026.

DG
CIK 0001839209 · last filed Jun 30, 2026
Total AUM
$3.8B
as of Q2 2026
Holdings
5
positions
Whale Score
73
73
strong
Activity
no data
changes this Q
AI Analysis · Q2 2026

Portfolio Overview

Darwin Global Management, Ltd. has undergone a radical transformation in its portfolio composition during the quarter ending September 30, 2025. The firm executed a complete overhaul of its investment strategy, reducing the total portfolio value by approximately 74.6%, from $2.38 billion to $605.08 million. This reduction was not merely a result of market performance but a deliberate strategic pivot evidenced by the liquidation of 100% of previous holdings. The portfolio ...

Key Holdings

The current portfolio is dominated by two major healthcare positions that account for over 96% of the total assets.

Analysis generated by 13F Insight from SEC Form 13F filing data · Q2 2026. Methodology

Quarter at a glance — Q2 2026

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q2 2026.

#HoldingValueSharesWeight
01
RVMD
REVOLUTION MEDICINES INC
$2.0B10.6M54.5%
02
INSM
INSMED INC
$674M6.4M17.9%
03
BLTE
BELITE BIO INC
$457M3.1M12.1%
04
ABVX
ABIVAX SA
$348M3.6M9.3%
05
G76279101
ROIVANT SCIENCES LTD
$234M6.7M6.2%

Filing history

2026Q2Jun 30
$3.8B 0.3%
5 positionsView →
2026Q1Mar 31
$3.8B 23.7%
6 positionsView →
2025Q4Dec 31
$4.9B 716.3%
6 positionsView →
2025Q3Sep 30
$605M 74.6%
3 positionsView →
2025Q2Jun 30
$2.4B
5 positionsLocked
2025Q1Mar 31
$0 100.0%
0 positionsLocked
2024Q4Dec 31
$1.1B 14.2%
6 positionsLocked
2024Q3Sep 30
$1.2B 43.1%
5 positionsLocked
2024Q2Jun 30
$859M 14.4%
9 positionsLocked
2024Q1Mar 31
$751M 47.4%
12 positionsLocked
2023Q4Dec 31
$509M 79.3%
8 positionsLocked
2023Q3Sep 30
$284M 53.5%
3 positionsLocked
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