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Filers›Asset Manager›EcoR1 Capital, LLC
DOSSIER · 13F-HR · Q1 2026

EcoR1 Capital, LLC

EcoR1's asset manager based in London, UK — $2.4B in tracked AUM across 30 positions as of Q1 2026.

E
EcoR1·London, UK·Asset Manager
CIK 0001587114 · last filed Mar 31, 2026
Total AUM
$2.4B
▲ 7.8%
vs prior
Holdings
30
—
positions
Whale Score
80
80
strong
Activity
—
no data
changes this Q
Top sector
Financials
43% weight
concentration
AI Analysis · Q1 2026 · Q1 2026

Portfolio Overview

EcoR1 Capital, LLC manages a concentrated, high-conviction investment portfolio totaling approximately $1.74 billion as of the report date September 30, 2025. The firm employs a focused strategy, holding only 23 positions, which indicates a preference for high selectivity over broad diversification. During the quarter, the portfolio experienced modest growth of +2.7%, increasing from $1.69 billion.

The portfolio is heavily skewed toward its top assets, with t...

Quarter at a glance — Q1 2026

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q1 2026.

#HoldingValueSharesWeight
01
ZYME
ZYMEWORKS INC
$575M23.0M24.4%
02
ANAB
ANAPTYSBIO INC
$437M7.9M18.5%
03
G50871105
JAZZ PHARMACEUTICALS PLC
$323M1.7M13.7%
04
CNTA
CENTESSA PHARMACEUTICALS PLC
$255M6.4M10.8%
05
CRNX
CRINETICS PHARMACEUTICALS IN
$156M4.3M6.6%
06
AKTS
AKTIS ONCOLOGY INC
$86M4.8M3.7%
07
ORIC
ORIC PHARMACEUTICALS INC
$85M6.7M3.6%
08
CGON
CG ONCOLOGY INC
$75M1.1M3.2%
09
H17182108
CRISPR THERAPEUTICS AG
$66M1.4M2.8%
10
ETON
ETON PHARMACEUTICALS INC
$54M2.2M2.3%

Filing history

Filing history loading…
AI Agent · grounded in EcoR1
haiku-4-5 · 30 positions indexed
Sector mix
  • Financials43%
  • Health Care8%
  • Cons. Disc.20%
  • Communications10%
  • Industrials17%
  • Energy6%
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