13F Insight
DOSSIER · 13F Holders · Q1 2026Healthcare · Pharmaceutical PreparationsCheap mega-capRe-rated
ZYME

ZYMEWORKS INC

224 institutions still hold ZYMEWORKS INC as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 98985Y108·Pharmaceutical Preparations·224 13F holders·last filed Mar 31, 2026
Market cap
—
▼ 4.0%
vs prior quarter
13F value held
$1.4B
59.0% inst. owned
of float
Holders
224
-16 QoQ
filers reporting
Activity
+22 / −10
+785 added · −770 reduced
this quarter
Concentration
40.11%
EcoR1 Capital, LLC #1
top holder share
AI Holders Summary · Q1 2026

224 institutions reported ZYME in Q1 2026. EcoR1 Capital, LLC leads at 40.1% of the visible book. -16 net institutions QoQ — distribution reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
EcoR1 Capital, LLC
CIK 0001587114
$575M23.0M24.41%Q1 202602
Rubric Capital Management LP
CIK 0001687509
$151M5.8M1.81%Q4 202503
BlackRock, Inc.
CIK 0002012383
$114M4.6M0.00%Q1 202604
BVF INC/IL
CIK 0001056807
$104M3.9M3.49%Q4 202505
PERCEPTIVE ADVISORS LLC
CIK 0001224962
$88M3.5M1.72%Q1 202606
MORGAN STANLEY
CIK 0000895421
$62M2.5M0.00%Q1 202607
BNP Paribas Asset Management Holding S.A.
CIK 0001520354
$48M1.9M0.06%Q1 202608
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$43M1.7M0.00%Q1 202609
Nextech Invest, Ltd.
CIK 0001595430
$29M1.1M2.84%Q4 202510
DIMENSIONAL FUND ADVISORS LP
CIK 0000354204· Quasi-passive
$29M1.1M0.01%Q1 202611
STATE STREET CORP
CIK 0000093751
$25M1.0M0.00%Q1 202612
Capricorn Fund Managers Ltd
CIK 0001901361
$25M1.0M3.93%Q1 202613
DEUTSCHE BANK AG\
CIK 0000948046
$23M921K0.01%Q1 202614
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP
CIK 0001164508
$19M744K0.01%Q1 202615
Assenagon Asset Management S.A.
CIK 0001546007
$18M728K0.03%Q1 202616
FMR LLC
CIK 0000315066
$17M667K0.00%Q1 202617
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$17M660K0.00%Q1 202618
Nuveen, LLC
CIK 0001871926
$16M652K0.00%Q1 202619
Nextech Invest Ltd.
CIK 0001911010
$16M1.1M2.65%Q4 202420
GOLDMAN SACHS GROUP INC
CIK 0000886982
$15M599K0.00%Q1 2026
Page 1 of 12
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