DOSSIER · 13F Holders · Q2 2026Healthcare · Pharmaceutical Preparations
ZYME

ZYMEWORKS INC

217 institutions still hold ZYMEWORKS INC as of Q2 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 98985Y108·Pharmaceutical Preparations·217 13F holders·last filed Jun 30, 2026
Market cap
13F value held
$1.5B
visible holders
Holders
217
filers reporting
Concentration
39.48%
EcoR1 Capital, LLC #1
top holder share
AI Holders Summary · Q2 2026

217 institutions reported ZYME in Q2 2026. EcoR1 Capital, LLC leads at 39.5% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
EcoR1 Capital, LLC
CIK 0001587114
$600M23.0M29.19%Q2 2026
02
Rubric Capital Management LP
CIK 0001687509
$183M7.0M1.68%Q2 2026
03
BlackRock, Inc.
CIK 0002012383
$111M4.3M0.00%Q2 2026
04
BVF INC/IL
CIK 0001056807
$104M3.9M3.49%Q4 2025
05
PERCEPTIVE ADVISORS LLC
CIK 0001224962
$88M3.5M1.72%Q1 2026
06
Assenagon Asset Management S.A.
CIK 0001546007· Quasi-passive
$65M2.5M0.04%Q2 2026
07
MORGAN STANLEY
CIK 0000895421
$58M2.2M0.00%Q2 2026
08
BNP Paribas Asset Management Holding S.A.
CIK 0001520354
$47M1.8M0.05%Q2 2026
09
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$41M1.6M0.00%Q2 2026
10
Nextech Invest, Ltd.
CIK 0001595430
$29M1.1M2.84%Q4 2025
11
STATE STREET CORP
CIK 0000093751
$28M1.1M0.00%Q2 2026
12
DIMENSIONAL FUND ADVISORS LP
CIK 0000354204· Quasi-passive
$26M995K0.00%Q2 2026
13
CITADEL ADVISORS LLC
CIK 0001423053
$25M966K0.00%Q2 2026
14
Delaware Management Holdings, Inc.
CIK 0000921739
$23M890K0.03%Q2 2026
15
FMR LLC
CIK 0000315066
$18M703K0.00%Q2 2026
16
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$18M692K0.00%Q2 2026
17
Qube Research & Technologies Ltd
CIK 0001729829
$16M594K0.01%Q2 2026
18
Prosight Management, LP
CIK 0001617201
$13M539K2.21%Q1 2026
19
Vanguard Portfolio Management
CIK 0002100121· Index
$13M510K0.00%Q2 2026
20
Capricorn Fund Managers Ltd
CIK 0001901361
$13M487K1.00%Q2 2026
Page 1 of 11
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Insiders at ZYMEWORKS INC
Hollywood MarkPlatshon ScottSchayowitz AdamStafford KristinGalbraith KennethCiongoli Gregory AustinLandry Robert EEcor1 Capital, Llc