DOSSIER · 13F-HR · Q1 2026

Enavate Sciences GP, LLC

$352M in tracked AUM across 7 positions as of Q1 2026.

ES
CIK 0001953107 · last filed Mar 31, 2026
Total AUM
$352M
as of Q1 2026
Holdings
7
positions
Whale Score
69
69
tracked
Activity
no data
changes this Q
AI Analysis · Q1 2026

Based on the SEC 13F filing data provided for Enavate Sciences GP, LLC as of September 30, 2025, here is a comprehensive analysis of the portfolio.

1. Portfolio Overview

Enavate Sciences GP, LLC manages a highly concentrated, high-conviction portfolio with a total value of $224.23 million. The fund exhibits a distinct lack of diversification, holding only five securities, with the top three positions accounting for over 82% of the total assets. The portfolio experienced significant growth d...

2. Key Holdings

The portfolio is dominated by biotechnology and pharmaceutical holdings, all of which appear to be in the clinical or development stage based on their market profiles.

  • Zenas Biopharma Inc (37.24%): This is the largest position, valued at $83.50 million (3.76M shares). As the anchor of the portfolio, Zenas represents a significant "bet" by the firm, indicating strong confidence in the company's clinical pipeline or regulatory progress.
  • Immunome Inc (24.90%): The second-largest holding, valued at $55.84 million (4.77M shares). Combined with Zenas, these two positions comprise over 62% of the fund's assets, suggesting that the manager favors specific therapeutic platforms or management teams within the immuno-oncology or biologics space.
  • Upstream Bio Inc (20.63%): Valued at $46.27 million (2.46M shares), this position reinforces the fund's strategy of holding substantial stakes in mid-cap biotech firms.
  • Compass Therapeutics Inc (12.16%): This position ($27.26M, 7.79M shares) is notable for having the highest share count among the top holdings, indicating a lower price point per share compared to the top three positions.
  • Camp4 Therapeutics Corp (5.07%): The smallest holding at $11.36 million (3.79M shares) rounds out the portfolio, completing the fund's exposure to the life sciences sector.

Quarter at a glance — Q1 2026

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q1 2026.

#HoldingValueSharesWeight
01
SION
SIONNA THERAPEUTICS INC
$99M2.5M28.3%
02
IMNM
IMMUNOME INC
$79M3.6M22.5%
03
ZBIO
ZENAS BIOPHARMA INC
$77M3.9M21.8%
04
CMPX
COMPASS THERAPEUTICS INC
$41M7.8M11.7%
05
BBOT
BRIDGEBIO ONCOLOGY THERAPEUT
$24M2.6M6.7%
06
UPB
UPSTREAM BIO INC
$22M2.5M6.3%
07
CAMP
CAMP4 THERAPEUTICS CORP
$10M2.2M2.7%

Filing history

2026Q1Mar 31
$352M 30.6%
7 positionsView →
2025Q4Dec 31
$507M 126.0%
7 positionsView →
2025Q3Sep 30
$224M 27.0%
5 positionsView →
2025Q2Jun 30
$177M 65.3%
6 positionsLocked
2025Q1Mar 31
$107M 23.3%
5 positionsLocked
2024Q4Dec 31
$139M
5 positionsLocked