AI Holders Summary · Q1 2026

148 institutions reported UPB in Q1 2026. FMR LLC leads at 21.2% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(3 on this page)

#HolderValueShares% port.Quarter

FMR LLC

CIK 0000315066

$73M8.1M0.00%Q1 2026 02

ORBIMED ADVISORS LLC

CIK 0001055951

$51M5.7M1.02%Q1 2026 03

VR Adviser, LLC

CIK 0001615982

$32M1.2M1.57%Q4 2025 04

BlackRock, Inc.

CIK 0002012383

$26M3.8M0.00%Q2 2026 05

Decheng Capital LLC

CIK 0002010850

$25M2.7M3.71%Q1 2026 06

Enavate Sciences GP, LLC

CIK 0001953107

$22M2.5M6.30%Q1 2026 07

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$17M1.9M0.00%Q1 2026 08

MARSHALL WACE, LLP

CIK 0001318757

$9M344K0.01%Q4 2025 09

FEDERATED HERMES, INC.

CIK 0001056288

$9M980K0.01%Q1 2026 10

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$9M951K0.00%Q1 2026 11

MILLENNIUM MANAGEMENT LLC

CIK 0001273087

$8M937K0.00%Q1 2026 12

GREAT POINT PARTNERS LLC

CIK 0001281446

$8M300K2.64%Q4 2025 13

Alyeska Investment Group, L.P.

CIK 0001453072

$8M298K0.02%Q4 2025 14

Bain Capital Life Sciences Investors, LLC

CIK 0001703031

$8M867K0.70%Q1 2026 15

Woodline Partners LP

CIK 0001784547

$7M831K0.03%Q1 2026 16

Parkman Healthcare Partners LLC

CIK 0001777015

$7M787K0.73%Q1 2026 17

Samsara BioCapital, LLC

CIK 0001744967

$7M736K0.64%Q1 2026 18

Vanguard Portfolio Management

CIK 0002100121· Index

$7M728K0.00%Q1 2026 19

Squadron Capital Management LLC

CIK 0002050709

$6M231K2.65%Q4 2025 20

SEB Asset Management AB

CIK 0002127509

$6M878K0.02%Q2 2026

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