DOSSIER · 13F-HR · Q1 2026

Omega Fund Management, LLC

Omega Fund's holding co. based in Omaha, NE — $163M in tracked AUM across 10 positions as of Q1 2026.

OF

Omega Fund·Omaha, NE·Holding Co.

CIK 0001637359 · last filed Mar 31, 2026

Total AUM

$163M

▼ 13.9%

vs prior

Holdings

10

—

positions

Whale Score

71

71

strong

Activity

—

no data

changes this Q

Top sector

Tech

52% weight

concentration

AI Analysis · Q1 2026 · Q1 2026

Based on the SEC 13F filing data provided for Omega Fund Management, LLC as of September 30, 2025, here is a comprehensive analysis of the portfolio's composition, activity, and strategic orientation.

1. Portfolio Overview

Omega Fund Management, LLC manages a concentrated, high-conviction portfolio totaling approximately $143.86 million across just 8 holdings. The portfolio is characterized by extreme concentration, with the top four positions accounting for roughly 94% of the total assets ...

Quarter at a glance — Q1 2026

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q1 2026.

#HoldingValueSharesWeight

01

Bicara Therapeutics Inc.

$48M2.4M29.2%

02

Nuvation Bio Inc.

$35M8.1M21.2%

03

BridgeBio Oncology Therapeutics Inc.

$29M3.3M18.0%

04

Kestra Med Technologies Ltd

$20M1.0M12.5%

05

Beta Bionics Inc.

$13M1.3M8.1%

06

enGene Holdings Inc.

$6M876K3.7%

07

Alumis Inc.

$5M241K3.3%

08

Sana Biotechnology, Inc.

$2M844K1.5%

09

ImageneBio, Inc.

$2M455K1.4%

10

Replimune Group

$2M249K1.2%

Filing history

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