DOSSIER · 13F-HR · Q1 2026

Sio Capital Management, LLC

Sio's asset manager based in Stamford, CT $697M in tracked AUM across 76 positions as of Q1 2026.

S
Sio·Stamford, CT·Asset Manager
CIK 0001482416 · last filed Mar 31, 2026
Total AUM
$697M
0.7%
vs prior
Holdings
76
positions
Whale Score
64
64
tracked
Activity
no data
changes this Q
Top sector
Financials
12% weight
concentration
AI Analysis · Q1 2026 · Q1 2026
Sio Capital Management, LLC – SEC 13F Filing Analysis

Report Period: Q3 2025 (Ended September 30, 2025)

1. Portfolio Overview

Sio Capital Management manages a concentrated portfolio valued at approximately $244.37 million, spread across 35 individual holdings. The firm executed a significant strategic pivot during the quarter, reducing the total portfolio value by 6.7% (down from $261.84 million in the previous quarter). This reduction was not merely a function of market pe...

Quarter at a glance — Q1 2026

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q1 2026.

#HoldingValueSharesWeight
01
MMS
MAXIMUS INC
$49M769K7.1%
02
WAY
WAYSTAR HLDG CORP
$40M1.6M5.7%
03
G4705A100
ICON PLC
$34M306K4.9%
04
COR
CENCORA INC
$32M101K4.5%
05
DNTH
DIANTHUS THERAPEUTICS INC
$31M370K4.5%
06
AVR
ANTERIS TECHNOLOGIES GLOBAL
$30M5.4M4.3%
07
CORT
CORCEPT THERAPEUTICS INC
$27M675K3.9%
08
G5509L101
LIVANOVA PLC
$27M422K3.8%
09
TYRA
TYRA BIOSCIENCES INC
$23M605K3.3%
10
CELC
CELCUITY INC
$22M194K3.2%

Filing history

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