13F Insight
DOSSIER · 13F Holders · Q1 2026Inflation hedgeYield
TYRA

TYRA BIOSCIENCES INC

170 institutions still hold TYRA BIOSCIENCES INC as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 90240B106·170 13F holders·last filed Mar 31, 2026
Market cap
—
▲ 2.5%
vs prior quarter
13F value held
$2.1B
63.0% inst. owned
of float
Holders
170
+93 QoQ
filers reporting
Activity
+36 / −84
+931 added · −756 reduced
this quarter
Concentration
22.44%
RA CAPITAL MANAGEMENT, L.P. #1
top holder share
AI Holders Summary · Q1 2026

170 institutions reported TYRA in Q1 2026. RA CAPITAL MANAGEMENT, L.P. leads at 22.4% of the visible book. +93 net new institutions vs prior quarter — accumulation reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
RA CAPITAL MANAGEMENT, L.P.
CIK 0001346824
$467M12.2M4.95%Q1 202602
FMR LLC
CIK 0000315066
$297M7.7M0.02%Q1 202603
JANUS HENDERSON GROUP PLC
CIK 0001274173
$149M3.9M0.07%Q1 202604
Alta Partners Management Company, L.P.
CIK 0002054419
$146M3.8M96.97%Q1 202605
FARALLON CAPITAL MANAGEMENT LLC
CIK 0000909661
$137M3.6M0.78%Q1 202606
TCG Crossover Management, LLC
CIK 0001839948
$124M3.2M3.56%Q1 202607
Nextech Invest, Ltd.
CIK 0001595430
$107M4.1M10.31%Q4 202508
Commodore Capital LP
CIK 0001831942
$95M2.5M5.48%Q1 202609
BlackRock, Inc.
CIK 0002012383
$85M2.2M0.00%Q1 202610
Paradigm Biocapital Advisors LP
CIK 0001855655
$79M2.1M1.61%Q1 202611
Nextech Invest Ltd.
CIK 0001911010
$56M4.1M9.15%Q4 202412
BVF INC/IL
CIK 0001056807
$56M2.1M1.88%Q4 202513
Caligan Partners LP
CIK 0001727492
$49M1.3M3.25%Q1 202614
STATE STREET CORP
CIK 0000093751
$47M1.2M0.00%Q1 202615
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$43M1.1M0.00%Q1 202616
Logos Global Management LP
CIK 0001792126
$33M850K1.63%Q1 202617
BARCLAYS PLC
CIK 0000312069
$32M833K0.01%Q1 202618
Canaan Partners XI LLC
CIK 0001850694
$29M750K37.76%Q1 202619
5AM Venture Management, LLC
CIK 0001799883
$27M1.0M8.51%Q4 202520
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$25M658K0.00%Q1 2026
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