DOSSIER · 13F-HR · Q1 2026

Caligan Partners LP

$1.5B in tracked AUM across 28 positions as of Q1 2026.

CP
CIK 0001727492 · last filed Mar 31, 2026
Total AUM
$1.5B
as of Q1 2026
Holdings
28
positions
Whale Score
70
70
strong
Activity
no data
changes this Q
AI Analysis · Q1 2026
Comprehensive Analysis of Caligan Partners LP SEC 13F Filing
Portfolio Overview

Caligan Partners LP manages a highly concentrated, high-conviction portfolio totaling approximately $606.23 million as of the report date September 30, 2025. The fund experienced significant growth during the quarter, with total assets under management (AUM) increasing by 16.5%, rising from $520.17 million in the previous quarter. The portfolio consists of only 15 holdings, indicating a strategy that prioritize...

Key Holdings

The portfolio is dominated by a few large positions, with the top three holdings comprising nearly 65% of the total assets.

  • Liquidia Corporation (LQDA) is the largest position, valued at $184.62 million, representing a massive 30.45% portfolio allocation. With 8.12 million shares held, this is clearly the firm's "conviction" bet.
  • ABIVAX SA (ABVX) is the second-largest holding at $123.27 million (20.33%), followed by Agios Pharmaceuticals Inc (AGIO) at $84.54 million (13.95%).
  • The top five positions are rounded out by Exelixis Inc (EXEL) at 10.39% and Revolution Medicines Inc (RVMD) at 8.20%.

The heavy weighting in LQDA and ABVX signals that the fund’s performance is highly correlated with the success of these specific companies. The inclusion of mid-cap and larger-cap names like EXEL alongside smaller developmental biotech companies suggests a blend of stability and high-growth potential within the healthcare universe.

Quarter at a glance — Q1 2026

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q1 2026.

#HoldingValueSharesWeight
01
LQDA
LIQUIDIA CORPORATION
$306M8.1M20.4%
02
RVMD
REVOLUTION MEDICINES INC
$183M1.9M12.2%
03
ABVX
ABIVAX SA
$163M1.5M10.8%
04
PCVX
VAXCYTE INC
$120M2.1M8.0%
05
XENE
XENON PHARMACEUTICALS INC
$81M1.4M5.4%
06
MLYS
MINERALYS THERAPEUTICS INC
$75M2.8M5.0%
07
EXEL
EXELIXIS INC
$67M1.6M4.4%
08
CGON
CG ONCOLOGY INC
$61M900K4.1%
09
TNGX
TANGO THERAPEUTICS INC
$50M2.4M3.4%
10
TYRA
TYRA BIOSCIENCES INC
$49M1.3M3.3%

Filing history

2026Q1Mar 31
$1.5B 23.7%
28 positionsView →
2025Q4Dec 31
$1.2B 100.4%
24 positionsView →
2025Q3Sep 30
$606M 16.5%
15 positionsView →
2025Q2Jun 30
$520M 61.6%
17 positionsLocked
2025Q1Mar 31
$322M 18.5%
12 positionsLocked
2024Q4Dec 31
$395M 25.2%
14 positionsLocked
2024Q3Sep 30
$315M 26.3%
12 positionsLocked
2024Q2Jun 30
$428M 13.1%
13 positionsLocked
2024Q1Mar 31
$378M 27.6%
12 positionsLocked
2023Q4Dec 31
$297M 36.2%
11 positionsLocked
2023Q3Sep 30
$218M 22.5%
13 positionsLocked
2023Q2Jun 30
$178M 24.0%
13 positionsLocked
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