DOSSIER · 13F Holders · Q1 2026Healthcare · Pharmaceutical PreparationsCyclicalNet sold
XENE

XENON PHARMACEUTICALS INC

299 institutions still hold XENON PHARMACEUTICALS INC as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 98420N105·Pharmaceutical Preparations·299 13F holders·last filed Mar 31, 2026
Market cap
3.9%
vs prior quarter
13F value held
$3.5B
68.0% inst. owned
of float
Holders
299
-116 QoQ
filers reporting
Activity
+76 / −34
+983 added · −810 reduced
this quarter
Concentration
17.83%
FMR LLC #1
top holder share
AI Holders Summary · Q1 2026

299 institutions reported XENE in Q1 2026. FMR LLC leads at 17.8% of the visible book. -116 net institutions QoQ — distribution reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
FMR LLC
CIK 0000315066
$629M10.8M0.03%Q1 2026
02
Avoro Capital Advisors LLC
CIK 0001633313
$336M5.8M3.31%Q1 2026
03
BlackRock, Inc.
CIK 0002012383
$328M5.6M0.01%Q1 2026
04
WELLINGTON MANAGEMENT GROUP LLP
CIK 0000902219
$281M4.8M0.05%Q1 2026
05
DRIEHAUS CAPITAL MANAGEMENT LLC
CIK 0000938206
$261M4.5M1.92%Q1 2026
06
Polar Capital Holdings Plc
CIK 0001837309
$256M4.4M0.91%Q1 2026
07
JANUS HENDERSON GROUP PLC
CIK 0001274173
$243M4.2M0.12%Q1 2026
08
Capital International Investors
CIK 0001562230
$156M2.7M0.04%Q1 2026
09
JPMORGAN CHASE & CO
CIK 0000019617
$107M1.9M0.01%Q1 2026
10
STATE STREET CORP
CIK 0000093751
$100M1.7M0.00%Q1 2026
11
SUSQUEHANNA INTERNATIONAL GROUP, LLP
CIK 0001446194· Market maker
$99M1.7M0.01%Q1 2026
12
Affinity Asset Advisors, LLC
CIK 0001773195
$97M1.7M5.03%Q1 2026
13
Holocene Advisors, LP
CIK 0001700574
$88M1.5M0.21%Q1 2026
14
WESTFIELD CAPITAL MANAGEMENT CO LP
CIK 0001177719
$81M1.4M0.34%Q1 2026
15
Caligan Partners LP
CIK 0001727492
$81M1.4M5.39%Q1 2026
16
BNP Paribas Asset Management Holding S.A.
CIK 0001520354
$78M1.3M0.09%Q1 2026
17
BRAIDWELL LP
CIK 0001920938
$78M1.3M2.60%Q1 2026
18
Caption Management, LLC
CIK 0001706766
$78M1.3M0.45%Q1 2026
19
Siren, L.L.C.
CIK 0002005245
$77M1.3M2.13%Q1 2026
20
FRANKLIN RESOURCES INC
CIK 0000038777
$74M1.3M0.02%Q1 2026
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