13F Insight
DOSSIER · 13F-HR · Q1 2026

SPHERA FUNDS MANAGEMENT LTD.

$630M in tracked AUM across 97 positions as of Q1 2026.

SF
CIK 0001496201 · last filed Mar 31, 2026
Total AUM
$630M
as of Q1 2026
Holdings
97
—
positions
Whale Score
53
53
tracked
Activity
—
no data
changes this Q
AI Analysis · Q1 2026

SPHERA FUNDS MANAGEMENT LTD. filed its latest 13F-HR for Q1 2026. See the latest holdings and position changes below.

Quarter at a glance — Q1 2026

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q1 2026.

#HoldingValueSharesWeight
01
MLYS
MINERALYS THERAPEUTICS INC
$36M1.3M5.8%02
TEVA
TEVA PHARMACEUTICAL INDS LTD
$34M1.1M5.4%03
M87915274
TOWER SEMICONDUCTOR LTD
$26M146K4.1%04
XBI
SPDR SERIES TRUST
$26M200K4.1%05
M7516K103
NOVA LTD
$23M53K3.7%06
CYTK
CYTOKINETICS INC
$20M299K3.1%07
BBIO
BRIDGEBIO PHARMA INC
$18M245K2.9%08
BIIB
BIOGEN INC
$17M93K2.7%09
RARE
ULTRAGENYX PHARMACEUTICAL IN
$17M809K2.7%10
SNDX
SYNDAX PHARMACEUTICALS INC
$17M725K2.7%

Filing history

2026Q1Mar 31
$630M▲ 21.7%
97 positionsView →2025Q4Dec 31
$517M▲ 80.1%
100 positionsView →2025Q3Sep 30
$287M▼ 32.6%
79 positionsView →2025Q2Jun 30
$426M▲ 53.9%
111 positionsLocked2025Q1Mar 31
$277M▼ 49.9%
85 positionsLocked2024Q4Dec 31
$553M▼ 12.0%
108 positionsLocked2024Q3Sep 30
$628M▼ 14.3%
116 positionsLocked2024Q2Jun 30
$733M▲ 3.0%
119 positionsLocked2024Q1Mar 31
$712M▲ 14.6%
105 positionsLocked2023Q4Dec 31
$621M▲ 13.2%
100 positionsLocked2023Q3Sep 30
$549M▼ 14.3%
83 positionsLocked2023Q2Jun 30
$640M▲ 7.0%
88 positionsLocked
Showing 12 of 48