13F Insight
DOSSIER · 13F Holders · Q1 2026Defensive growthQuality
DSGN

DESIGN THERAPEUTICS INC

126 institutions still hold DESIGN THERAPEUTICS INC as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 25056L103·126 13F holders·last filed Mar 31, 2026
Market cap
—
▼ 8.4%
vs prior quarter
13F value held
$328M
72.0% inst. owned
of float
Holders
126
+54 QoQ
filers reporting
Activity
+46 / −55
+887 added · −754 reduced
this quarter
Concentration
21.18%
SR ONE CAPITAL MANAGEMENT, LP #1
top holder share
AI Holders Summary · Q1 2026

126 institutions reported DSGN in Q1 2026. SR ONE CAPITAL MANAGEMENT, LP leads at 21.2% of the visible book. +54 net new institutions vs prior quarter — accumulation reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
SR ONE CAPITAL MANAGEMENT, LP
CIK 0001910264
$69M6.5M7.59%Q1 202602
RA CAPITAL MANAGEMENT, L.P.
CIK 0001346824
$32M3.0M0.34%Q1 202603
Point72 Asset Management, L.P.
CIK 0001603466
$29M2.7M0.04%Q1 202604
BlackRock, Inc.
CIK 0002012383
$23M2.1M0.00%Q1 202605
BAKER BROS. ADVISORS LP
CIK 0001263508
$21M2.2M0.12%Q4 202506
Logos Global Management LP
CIK 0001792126
$21M1.9M1.04%Q1 202607
DRIEHAUS CAPITAL MANAGEMENT LLC
CIK 0000938206
$19M1.7M0.14%Q1 202608
Vivo Capital, LLC
CIK 0001674712
$17M1.6M1.43%Q1 202609
Almitas Capital LLC
CIK 0001596468
$16M1.5M3.68%Q1 202610
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$14M1.3M0.00%Q1 202611
Woodline Partners LP
CIK 0001784547
$10M962K0.04%Q1 202612
FMR LLC
CIK 0000315066
$8M798K0.00%Q1 202613
Kynam Capital Management, LP
CIK 0001907884
$8M785K0.52%Q1 202614
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$7M693K0.00%Q1 202615
STATE STREET CORP
CIK 0000093751
$7M660K0.00%Q1 202616
MORGAN STANLEY
CIK 0000895421
$7M657K0.00%Q1 202617
GOLDMAN SACHS GROUP INC
CIK 0000886982
$5M505K0.00%Q1 202618
DIMENSIONAL FUND ADVISORS LP
CIK 0000354204· Quasi-passive
$5M432K0.00%Q1 202619
RENAISSANCE TECHNOLOGIES LLC
CIK 0001037389
$4M408K0.01%Q1 202620
CITADEL ADVISORS LLC
CIK 0001423053
$4M460K0.00%Q4 2025
Page 1 of 7
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