13F Insight
DOSSIER · 13F Holders · Q1 2026High-convictionMulti-bagger
DYN

Dyne Therapeutics Inc

235 institutions still hold Dyne Therapeutics Inc as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 26818m108·235 13F holders·last filed Mar 31, 2026
Market cap
—
▲ 0.4%
vs prior quarter
13F value held
$2.0B
48.0% inst. owned
of float
Holders
235
-72 QoQ
filers reporting
Activity
+10 / −76
+859 added · −707 reduced
this quarter
Concentration
12.67%
JANUS HENDERSON GROUP PLC #1
top holder share
AI Holders Summary · Q1 2026

235 institutions reported DYN in Q1 2026. JANUS HENDERSON GROUP PLC leads at 12.7% of the visible book. -72 net institutions QoQ — distribution reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
JANUS HENDERSON GROUP PLC
CIK 0001274173
$247M13.6M0.12%Q1 202602
BlackRock, Inc.
CIK 0002012383
$212M11.7M0.00%Q1 202603
Atlas Venture Life Science Advisors, LLC
CIK 0001917529
$166M9.1M20.95%Q1 202604
FMR LLC
CIK 0000315066
$162M8.9M0.01%Q1 202605
Orbis Allan Gray Ltd
CIK 0001663865
$123M6.8M0.52%Q1 202606
STATE STREET CORP
CIK 0000093751
$121M6.7M0.00%Q1 202607
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$116M6.4M0.00%Q1 202608
PERCEPTIVE ADVISORS LLC
CIK 0001224962
$85M4.7M1.65%Q1 202609
FCPM III SERVICES B.V.
CIK 0002013410
$84M4.6M11.66%Q1 202610
TCG Crossover Management, LLC
CIK 0001839948
$84M4.6M2.39%Q1 202611
Vanguard Portfolio Management
CIK 0002100121
$75M4.2M0.00%Q1 202612
Vestal Point Capital, LP
CIK 0001974915
$73M4.0M2.03%Q1 202613
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$64M3.5M0.00%Q1 202614
ARMISTICE CAPITAL, LLC
CIK 0001601086
$58M3.2M1.02%Q1 202615
Frazier Life Sciences Management, L.P.
CIK 0001892134
$57M3.2M1.47%Q1 202616
JPMORGAN CHASE & CO
CIK 0000019617
$56M3.3M0.00%Q1 202617
ORBIMED ADVISORS LLC
CIK 0001055951
$53M2.9M1.05%Q1 202618
VR Adviser, LLC
CIK 0001615982
$43M2.2M2.10%Q4 202519
Siren, L.L.C.
CIK 0002005245
$40M2.2M1.12%Q1 202620
FRANKLIN RESOURCES INC
CIK 0000038777
$36M2.0M0.01%Q1 2026
Page 1 of 12
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