AI Holders Summary · Q4 2025

144 institutions reported LXEO in Q4 2025. CITADEL ADVISORS LLC leads at 9.6% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(2 on this page)

#HolderValueShares% port.Quarter

CITADEL ADVISORS LLC

CIK 0001423053

$37M3.8M0.01%Q4 2025 02

Paradigm Biocapital Advisors LP

CIK 0001855655

$35M6.2M0.73%Q1 2026 03

BlackRock, Inc.

CIK 0002012383

$29M5.1M0.00%Q1 2026 04

Affinity Asset Advisors, LLC

CIK 0001773195

$29M5.1M1.50%Q1 2026 05

RA CAPITAL MANAGEMENT, L.P.

CIK 0001346824

$29M5.0M0.30%Q1 2026 06

JANUS HENDERSON GROUP PLC

CIK 0001274173

$29M5.0M0.01%Q1 2026 07

Vestal Point Capital, LP

CIK 0001974915

$26M4.5M0.72%Q1 2026 08

Frazier Life Sciences Management, L.P.

CIK 0001892134

$25M4.4M0.65%Q1 2026 09

ORBIMED ADVISORS LLC

CIK 0001055951

$21M3.6M0.41%Q1 2026 10

STATE STREET CORP

CIK 0000093751

$20M3.6M0.00%Q1 2026 11

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$17M3.0M0.00%Q1 2026 12

Woodline Partners LP

CIK 0001784547

$16M2.8M0.06%Q1 2026 13

GOLDMAN SACHS GROUP INC

CIK 0000886982

$11M1.9M0.00%Q1 2026 14

683 Capital Management, LLC

CIK 0001404574

$11M1.1M0.48%Q4 2025 15

Avoro Capital Advisors LLC

CIK 0001633313

$11M1.9M0.11%Q1 2026 16

Point72 Asset Management, L.P.

CIK 0001603466

$10M1.7M0.01%Q1 2026 17

MILLENNIUM MANAGEMENT LLC

CIK 0001273087

$9M1.6M0.00%Q1 2026 18

BALYASNY ASSET MANAGEMENT L.P.

CIK 0001218710

$9M1.6M0.01%Q1 2026 19

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$9M1.5M0.00%Q1 2026 20

ADAR1 Capital Management, LLC

CIK 0001940272

$8M1.5M0.50%Q1 2026

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