AI Holders Summary · Q1 2026

71 institutions reported OBIO in Q1 2026. RTW INVESTMENTS, LP leads at 38.3% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(5 on this page)

#HolderValueShares% port.Quarter

RTW INVESTMENTS, LP

CIK 0001493215

$35M8.3M0.35%Q1 2026 02

PERCEPTIVE ADVISORS LLC

CIK 0001224962

$21M5.0M0.42%Q1 2026 03

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$9M2.2M0.00%Q1 2026 04

Alyeska Investment Group, L.P.

CIK 0001453072

$4M1.0M0.01%Q4 2025 05

Propel Bio Management, LLC

CIK 0001969764

$4M897K2.41%Q1 2026 06

MILLENNIUM MANAGEMENT LLC

CIK 0001273087

$3M703K0.00%Q1 2026 07

BlackRock, Inc.

CIK 0002012383

$3M636K0.00%Q1 2026 08

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$2M485K0.00%Q1 2026 09

Affinity Asset Advisors, LLC

CIK 0001773195

$2M403K0.09%Q1 2026 10

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

CIK 0000884546· Index

$1M265K0.00%Q1 2026 11

Knott David M Jr

CIK 0001892770

$1M254K0.64%Q1 2026 12

VANGUARD FIDUCIARY TRUST CO

CIK 0000933478· Index

$1000K235K0.00%Q1 2026 13

Simplify Asset Management Inc.

CIK 0001846368

$947K219K0.01%Q2 2026 14

683 Capital Management, LLC

CIK 0001404574

$847K204K0.04%Q4 2025 15

STATE STREET CORP

CIK 0000093751

$720K169K0.00%Q1 2026 16

MARSHALL WACE, LLP

CIK 0001318757

$712K172K0.00%Q4 2025 17

GOLDMAN SACHS GROUP INC

CIK 0000886982

$660K155K0.00%Q1 2026 18

DAFNA Capital Management LLC

CIK 0001389933

$539K127K0.12%Q1 2026 19

NORTHERN TRUST CORP

CIK 0000073124· Index

$503K118K0.00%Q1 2026 20

Qube Research & Technologies Ltd

CIK 0001729829

$463K109K0.00%Q1 2026

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