13F Insight
DOSSIER · 13F Holders · Q4 2025Cheap mega-capRe-rated
SERA

SERA PROGNOSTICS INC

57 institutions still hold SERA PROGNOSTICS INC as of Q4 2025. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 81749D107·57 13F holders·last filed Dec 31, 2025
Market cap
—
▲ 0.5%
vs prior quarter
13F value held
$49M
71.0% inst. owned
of float
Holders
57
-30 QoQ
filers reporting
Activity
+84 / −6
+893 added · −739 reduced
this quarter
Concentration
33.10%
BAKER BROS. ADVISORS LP #1
top holder share
AI Holders Summary · Q4 2025

57 institutions reported SERA in Q4 2025. BAKER BROS. ADVISORS LP leads at 33.1% of the visible book. -30 net institutions QoQ — distribution reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
BAKER BROS. ADVISORS LP
CIK 0001263508
$16M5.5M0.10%Q4 202502
Whetstone Capital Advisors, LLC
CIK 0001607278
$10M3.5M3.33%Q4 202503
Aberdeen Group plc
CIK 0001716774
$5M2.6M0.01%Q1 202604
PSP Research LLC
CIK 0002106939
$5M2.4M3.44%Q1 202605
Vivo Capital, LLC
CIK 0001674712
$3M1.7M0.28%Q1 202606
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$2M1.2M0.00%Q1 202607
CITADEL ADVISORS LLC
CIK 0001423053
$2M708K0.00%Q4 202508
CAPTRUST FINANCIAL ADVISORS
CIK 0001512024
$1M537K0.00%Q1 202609
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$738,511364K0.00%Q1 202610
SANDERS MORRIS HARRIS LLC
CIK 0001053994
$639,349315K0.10%Q1 202611
AWM Investment Company, Inc.
CIK 0001535264
$420,985207K0.05%Q1 202612
BlackRock, Inc.
CIK 0002012383
$398,093196K0.00%Q1 202613
VANGUARD FIDUCIARY TRUST CO
CIK 0000933478· Index
$344,412170K0.00%Q1 202614
STATE STREET CORP
CIK 0000093751
$253,328125K0.00%Q1 202615
MORGAN STANLEY
CIK 0000895421
$213,184105K0.00%Q1 202616
NORTHERN TRUST CORP
CIK 0000073124· Index
$195,96697K0.00%Q1 202617
MILLENNIUM MANAGEMENT LLC
CIK 0001273087
$185,75392K0.00%Q1 202618
Perigon Wealth Management, LLC
CIK 0001575239
$147,55173K0.00%Q1 202619
Bank of New York Mellon Corp
CIK 0001390777
$123,68261K0.00%Q1 202620
Requisite Capital Management, LLC
CIK 0001730573
$112,96556K0.02%Q1 2026
Page 1 of 3
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