AI Holders Summary · Q2 2026

27 institutions reported XLO in Q2 2026. Bain Capital Life Sciences Investors, LLC leads at 23.8% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(3 on this page)

#HolderValueShares% port.Quarter

Bain Capital Life Sciences Investors, LLC

CIK 0001703031

$6M664K0.38%Q2 2026 02

ORBIMED ADVISORS LLC

CIK 0001055951

$6M592K0.11%Q2 2026 03

Frazier Life Sciences Management, L.P.

CIK 0001892134

$4M423K0.09%Q2 2026 04

Stonepine Capital Management, LLC

CIK 0001440771

$2M226K1.22%Q2 2026 05

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$2M179K0.00%Q2 2026 06

Sio Capital Management, LLC

CIK 0001482416

$1M152K0.24%Q2 2026 07

ADAGE CAPITAL PARTNERS GP, L.L.C.

CIK 0001165408

$1M112K0.00%Q2 2026 08

Merck & Co., Inc.

CIK 0000310158

$1M106K0.19%Q2 2026 09

RENAISSANCE TECHNOLOGIES LLC

CIK 0001037389

$615K64K0.00%Q2 2026 10

MORGAN STANLEY

CIK 0000895421

$546K57K0.00%Q2 2026 11

AJU IB Investment Co., Ltd.

CIK 0001710065

$401K48K1.31%Q1 2026 12

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$374K39K0.00%Q2 2026 13

CITADEL ADVISORS LLC

CIK 0001423053

$249K26K0.00%Q2 2026 14

VANGUARD FIDUCIARY TRUST CO

CIK 0000933478· Index

$216K23K0.00%Q2 2026 15

BRIDGEWAY CAPITAL MANAGEMENT, LLC

CIK 0001107261

$168K18K0.00%Q2 2026 16

GSA CAPITAL PARTNERS LLP

CIK 0001362033

$143K17K0.01%Q1 2026 17

TWO SIGMA INVESTMENTS, LP

CIK 0001179392

$139K15K0.00%Q2 2026 18

Velan Capital Investment Management LP

CIK 0001848809

$137K14K0.08%Q2 2026 19

STATE STREET CORP

CIK 0000093751

$128K13K0.00%Q2 2026 20

PRELUDE CAPITAL MANAGEMENT, LLC

CIK 0001387508

$111K12K0.01%Q2 2026

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