What does DAFNA Capital Management LLC hold? Q1 2026 13F Holdings & Portfolio

AI Analysis · Q1 2026 · Q1 2026

Comprehensive Analysis of DAFNA Capital Management LLC SEC 13F Filing Report Period: Q3 2025 (Ended September 30, 2025)

1. Portfolio Overview

DAFNA Capital Management LLC manages a concentrated portfolio with a total value of approximately $335.63 million spread across 52 holdings. The firm employs a high-conviction investment strategy, evidenced by the fact that the top ten positions account for nearly 70% of the total portfolio value.

For the quarter, the portfolio ex...

Quarter at a glance — Q1 2026

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q1 2026.

#HoldingValueSharesWeight

RVMD

REVOLUTION MEDICINES INC

$56M581K12.8%

XBI

SPDR S&P BIOTECH ETF

$41M319K9.3%

STXS

STEREOTAXIS INC

$25M13.7M5.7%

DAWN

DAY ONE BIOPHARMACEUTICALS I

$21M978K4.8%

ATRC

ATRICURE INC

$17M597K3.9%

IDYA

IDEAYA BIOSCIENCES INC

$16M477K3.6%

XENE

XENON PHARMACEUTICALS INC

$15M251K3.3%

CYTK

CYTOKINETICS INC

$14M217K3.3%

CMPS

COMPASS PATHWAYS PLC

$13M2.4M3.0%

NKTR

NEKTAR THERAPEUTICS

$12M165K2.7%

Filing history

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