Name: Flagship Pioneering Inc. 13F Holdings
Creator: 13F Insight

AI Analysis · Q4 2025

Portfolio Overview

Flagship Pioneering Inc.’s SEC 13F filing for the period ending September 30, 2025, reveals a highly concentrated and specialized investment portfolio. The total portfolio value decreased substantially by 47.1%, contracting from approximately $268.47 million in the previous quarter to $141.89 million. This reduction is not solely attributable to market depreciation but is primarily driven by significant capital reallocation, evidenced by the liquidation of two major posit...

Analysis generated by 13F Insight from SEC Form 13F filing data · Q4 2025. Methodology

Quarter at a glance — Q4 2025

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q4 2025.

#HoldingValueSharesWeight

Sana Biotechnology Inc

$102M25.0M31.4%03

FHTX

Foghorn Therapeutics Inc

$68M12.7M21.1%04

MCRB

Seres Therapeutics Inc

$17M1.2M5.3%

Filing history

2025Q4Dec 31

$324M▲ 128.4%

6 positionsView →2025Q3Sep 30

$142M▼ 47.1%

4 positionsLocked 2025Q2Jun 30

$268M▲ 82.0%

8 positionsLocked 2025Q1Mar 31

$148M▼ 55.9%

4 positionsLocked 2024Q4Dec 31

$334M▼ 43.5%

10 positionsLocked 2024Q3Sep 30

$592M▼ 29.8%

12 positionsLocked 2024Q2Jun 30

$843M▼ 44.7%

12 positionsLocked 2024Q1Mar 31

$1.5B▲ 15.0%

13 positionsLocked 2023Q4Dec 31

$1.3B▼ 3.8%

13 positionsLocked 2023Q3Sep 30

$1.4B▼ 38.5%

18 positionsLocked 2023Q2Jun 30

$2.2B▼ 12.9%

20 positionsLocked 2023Q1Mar 31

$2.6B▼ 17.8%

22 positionsLocked

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