AI Holders Summary · Q4 2025

110 institutions reported FHTX in Q4 2025. Flagship Pioneering Inc. leads at 32.9% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(5 on this page)

#HolderValueShares% port.Quarter

Flagship Pioneering Inc.

CIK 0001400240

$68M12.7M21.12%Q4 2025 02

FMR LLC

CIK 0000315066

$29M6.0M0.00%Q1 2026 03

BVF INC/IL

CIK 0001056807

$29M5.3M0.96%Q4 2025 04

DEERFIELD MANAGEMENT COMPANY, L.P.

CIK 0001009258

$20M3.6M0.25%Q4 2025 05

RAYMOND JAMES FINANCIAL INC

CIK 0000720005

$12M2.6M0.00%Q1 2026 06

BlackRock, Inc.

CIK 0002012383

$11M2.4M0.00%Q1 2026 07

Euclidean Capital LLC

CIK 0001825034

$8M1.6M1.92%Q1 2026 08

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$7M1.5M0.00%Q1 2026 09

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$4M848K0.00%Q1 2026 10

Siren, L.L.C.

CIK 0002005245

$3M721K0.10%Q1 2026 11

STATE STREET CORP

CIK 0000093751

$3M680K0.00%Q1 2026 12

AMERIPRISE FINANCIAL INC

CIK 0000820027

$2M449K0.00%Q1 2026 13

RENAISSANCE TECHNOLOGIES LLC

CIK 0001037389

$2M406K0.00%Q1 2026 14

Candriam S.C.A.

CIK 0001537014

$1M314K0.01%Q1 2026 15

JACOBS LEVY EQUITY MANAGEMENT, INC

CIK 0000884414

$1M304K0.01%Q1 2026 16

Birchview Capital, LP

CIK 0001618205

$1M282K0.77%Q1 2026 17

NORTHERN TRUST CORP

CIK 0000073124· Index

$1M276K0.00%Q1 2026 18

Vanguard Portfolio Management

CIK 0002100121· Index

$1M256K0.00%Q1 2026 19

VANGUARD FIDUCIARY TRUST CO

CIK 0000933478· Index

$1M241K0.00%Q1 2026 20

CITADEL ADVISORS LLC

CIK 0001423053

$984K182K0.00%Q4 2025

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