AI Holders Summary · Q4 2025

39 institutions reported MCRB in Q4 2025. Flagship Pioneering Inc. leads at 61.8% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(6 on this page)

#HolderValueShares% port.Quarter

Flagship Pioneering Inc.

CIK 0001400240

$17M1.2M5.32%Q4 2025 02

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$2M288K0.00%Q2 2026 03

MARSHALL WACE, LLP

CIK 0001318757

$1M172K0.00%Q2 2026 04

SUSQUEHANNA INTERNATIONAL GROUP, LLP

CIK 0001446194· Market maker

$1M133K0.00%Q2 2026 05

Vontobel Holding Ltd.

CIK 0001588340

$970K123K0.00%Q2 2026 06

BlackRock, Inc.

CIK 0002012383

$876K111K0.00%Q2 2026 07

683 Capital Management, LLC

CIK 0001404574

$778K52K0.03%Q4 2025 08

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$631K80K0.00%Q2 2026 09

CITADEL ADVISORS LLC

CIK 0001423053

$426K54K0.00%Q2 2026 10

VANGUARD FIDUCIARY TRUST CO

CIK 0000933478· Index

$384K49K0.00%Q2 2026 11

HAP TRADING, LLC

CIK 0001049854

$335K125K0.02%Q3 2025 12

STATE STREET CORP

CIK 0000093751

$267K34K0.00%Q2 2026 13

Lion Point Capital, LP

CIK 0001643354

$249K32K1.19%Q2 2026 14

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

CIK 0000884546· Index

$245K31K0.00%Q2 2026 15

AMERICAN CENTURY COMPANIES INC

CIK 0000748054

$223K28K0.00%Q2 2026 16

XTX Topco Ltd

CIK 0001828301

$164K21K0.00%Q2 2026 17

GOLDMAN SACHS GROUP INC

CIK 0000886982

$120K15K0.00%Q2 2026 18

NORTHERN TRUST CORP

CIK 0000073124· Index

$116K15K0.00%Q2 2026 19

Invesco Ltd.

CIK 0000914208

$102K13K0.00%Q2 2026 20

MORGAN STANLEY

CIK 0000895421

$96K12K0.00%Q2 2026

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