AI Holders Summary · Q4 2025

35 institutions reported MCRB in Q4 2025. Flagship Pioneering Inc. leads at 55.4% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(6 on this page)

#HolderValueShares% port.Quarter

Flagship Pioneering Inc.

CIK 0001400240

$17M1.2M5.32%Q4 2025 02

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$3M294K0.00%Q1 2026 03

SUSQUEHANNA INTERNATIONAL GROUP, LLP

CIK 0001446194· Market maker

$2M227K0.00%Q1 2026 04

MARSHALL WACE, LLP

CIK 0001318757

$2M120K0.00%Q4 2025 05

Vontobel Holding Ltd.

CIK 0001588340

$1M138K0.00%Q1 2026 06

CITADEL ADVISORS LLC

CIK 0001423053

$1M74K0.00%Q4 2025 07

BlackRock, Inc.

CIK 0002012383

$905K102K0.00%Q1 2026 08

683 Capital Management, LLC

CIK 0001404574

$778K52K0.03%Q4 2025 09

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$664K75K0.00%Q1 2026 10

AMERICAN CENTURY COMPANIES INC

CIK 0000748054

$553K62K0.00%Q1 2026 11

VANGUARD FIDUCIARY TRUST CO

CIK 0000933478· Index

$352K40K0.00%Q1 2026 12

HAP TRADING, LLC

CIK 0001049854

$335K125K0.02%Q3 2025 13

STATE STREET CORP

CIK 0000093751

$301K34K0.00%Q1 2026 14

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

CIK 0000884546· Index

$281K32K0.00%Q1 2026 15

Lion Point Capital, LP

CIK 0001643354

$280K32K1.67%Q1 2026 16

MORGAN STANLEY

CIK 0000895421

$192K22K0.00%Q1 2026 17

TWO SIGMA INVESTMENTS, LP

CIK 0001179392

$167K19K0.00%Q1 2026 18

NORTHERN TRUST CORP

CIK 0000073124· Index

$131K15K0.00%Q1 2026 19

Invesco Ltd.

CIK 0000914208

$129K15K0.00%Q1 2026 20

UBS Group AG

CIK 0001610520

$62K7K0.00%Q1 2026

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