DOSSIER · 13F-HR · Q4 2025

VR Adviser, LLC

VR Adviser's holding co. based in Stamford, CT $2.0B in tracked AUM across 27 positions as of Q4 2025.

VA
VR Adviser·Stamford, CT·Holding Co.
CIK 0001615982 · last filed Dec 31, 2025
Total AUM
$2.0B
6.5%
vs prior
Holdings
27
positions
Whale Score
66
66
tracked
Activity
no data
changes this Q
Top sector
Financials
48% weight
concentration
AI Analysis · Q4 2025 · Q4 2025

Portfolio Overview

VR Adviser, LLC manages a concentrated, high-conviction portfolio totaling approximately $1.28 billion as of the report date September 30, 2025. The fund experienced a slight contraction in value, decreasing by 3.9% from the previous quarter's $1.33 billion. This decline is attributable to a combination of market performance and active capital reallocation, as the manager exited eight positions totaling approximately $316 million in value. The portfolio is highly concentr...

Quarter at a glance — Q4 2025

Position-change comparison pending.

No quarter-over-quarter changes available.

Top 10 holdings

By portfolio weight as of Q4 2025.

#HoldingValueSharesWeight
01
APGE
APOGEE THERAPEUTICS INC
$641M8.5M31.7%
02
ORKA
ORUKA THERAPEUTICS INC
$126M4.1M6.2%
03
VRDN
VIRIDIAN THERAPEUTICS INC
$121M3.9M6.0%
04
SYRE
SPYRE THERAPEUTICS INC
$121M3.7M6.0%
05
KALV
KALVISTA PHARMACEUTICALS INC
$109M6.7M5.4%
06
OCUL
OCULAR THERAPEUTIX INC
$89M7.3M4.4%
07
SVRA
SAVARA INC
$83M13.7M4.1%
08
COGT
COGENT BIOSCIENCES INC
$71M2.0M3.5%
09
ERAS
ERASCA INC
$66M17.9M3.3%
10
CTMX
CYTOMX THERAPEUTICS INC
$66M15.6M3.3%

Filing history

Filing history loading…