DOSSIER · 13F Holders · Q1 2026High-convictionMulti-bagger
ORKA

ORUKA THERAPEUTICS INC

186 institutions still hold ORUKA THERAPEUTICS INC as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 687604108·186 13F holders·last filed Mar 31, 2026
Market cap
8.2%
vs prior quarter
13F value held
$2.0B
70.0% inst. owned
of float
Holders
186
+14 QoQ
filers reporting
Activity
+34 / −30
+940 added · −913 reduced
this quarter
Concentration
18.59%
FMR LLC #1
top holder share
AI Holders Summary · Q1 2026

186 institutions reported ORKA in Q1 2026. FMR LLC leads at 18.6% of the visible book. +14 net new institutions vs prior quarter — accumulation reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
FMR LLC
CIK 0000315066
$365M7.4M0.02%Q1 2026
02
Fairmount Funds Management LLC
CIK 0001802528
$182M3.7M13.13%Q1 2026
03
BlackRock, Inc.
CIK 0002012383
$173M3.5M0.00%Q1 2026
04
VIKING GLOBAL INVESTORS LP
CIK 0001103804
$131M2.7M0.37%Q1 2026
05
VR Adviser, LLC
CIK 0001615982
$126M4.1M6.21%Q4 2025
06
Paradigm Biocapital Advisors LP
CIK 0001855655
$114M2.3M2.33%Q1 2026
07
RTW INVESTMENTS, LP
CIK 0001493215
$101M2.1M1.00%Q1 2026
08
Deep Track Capital, LP
CIK 0001856083
$100M2.0M1.63%Q1 2026
09
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$91M1.9M0.00%Q1 2026
10
Avidity Partners Management LP
CIK 0001791827
$89M1.5M9.55%Q1 2026
11
STATE STREET CORP
CIK 0000093751
$79M1.6M0.00%Q1 2026
12
Remedium Capital Partners, LLC
CIK 0002104501
$77M1.6M27.31%Q1 2026
13
PERCEPTIVE ADVISORS LLC
CIK 0001224962
$68M1.4M1.34%Q1 2026
14
Polar Capital Holdings Plc
CIK 0001837309
$51M1.0M0.18%Q1 2026
15
FRANKLIN RESOURCES INC
CIK 0000038777
$49M1.0M0.01%Q1 2026
16
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$47M955K0.00%Q1 2026
17
MERCER GLOBAL ADVISORS INC /ADV
CIK 0000853758
$39M802K0.06%Q1 2026
18
Woodline Partners LP
CIK 0001784547
$28M575K0.11%Q1 2026
19
Cormorant Asset Management, LP
CIK 0001583977
$26M533K1.31%Q1 2026
20
Affinity Asset Advisors, LLC
CIK 0001773195
$25M500K1.27%Q1 2026
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