AI Holders Summary · Q1 2026

50 institutions reported ACET in Q1 2026. RA CAPITAL MANAGEMENT, L.P. leads at 20.2% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(2 on this page)

#HolderValueShares% port.Quarter

RA CAPITAL MANAGEMENT, L.P.

CIK 0001346824

$8M1.2M0.09%Q1 2026 02

ORBIMED ADVISORS LLC

CIK 0001055951

$7M1.0M0.14%Q1 2026 03

FRANKLIN RESOURCES INC

CIK 0000038777

$4M627K0.00%Q1 2026 04

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$2M337K0.00%Q1 2026 05

Woodline Partners LP

CIK 0001784547

$2M313K0.01%Q1 2026 06

ADAGE CAPITAL PARTNERS GP, L.L.C.

CIK 0001165408

$2M274K0.00%Q1 2026 07

Alyeska Investment Group, L.P.

CIK 0001453072

$2M204K0.00%Q4 2025 08

Prosight Management, LP

CIK 0001617201

$2M250K0.28%Q1 2026 09

RENAISSANCE TECHNOLOGIES LLC

CIK 0001037389

$2M233K0.00%Q1 2026 10

Stonepine Capital Management, LLC

CIK 0001440771

$2M222K0.61%Q1 2026 11

Carlyle Group Inc.

CIK 0001527166

$1M184K0.01%Q1 2026 12

NEXTBio Capital Management LP

CIK 0002038158

$1M158K0.50%Q1 2026 13

TWO SIGMA ADVISERS, LP

CIK 0001478735

$937K111K0.00%Q4 2025 14

CITADEL ADVISORS LLC

CIK 0001423053

$908K108K0.00%Q4 2025 15

ACADIAN ASSET MANAGEMENT LLC

CIK 0000916542

$802K118K0.00%Q1 2026 16

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$689K101K0.00%Q1 2026 17

DAFNA Capital Management LLC

CIK 0001389933

$639K94K0.15%Q1 2026 18

Burkehill Global Management, LP

CIK 0001904549

$526K63K0.03%Q4 2025 19

LUMINUS MANAGEMENT LLC

CIK 0001279151

$501K60K0.44%Q4 2025 20

Rangeley Capital, LLC

CIK 0001517796

$381K56K0.37%Q1 2026

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