13F Insight
DOSSIER · 13F Holders · Q4 2025Cheap mega-capRe-rated
ACOG

ALPHA COGNITION INC

28 institutions still hold ALPHA COGNITION INC as of Q4 2025. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 02074j501·28 13F holders·last filed Dec 31, 2025
Market cap
—
▼ 1.5%
vs prior quarter
13F value held
$58M
51.0% inst. owned
of float
Holders
28
-113 QoQ
filers reporting
Activity
+56 / −12
+856 added · −768 reduced
this quarter
Concentration
23.14%
Opaleye Management Inc. #1
top holder share
AI Holders Summary · Q4 2025

28 institutions reported ACOG in Q4 2025. Opaleye Management Inc. leads at 23.1% of the visible book. -113 net institutions QoQ — distribution reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
Opaleye Management Inc.
CIK 0001595855
$13M2.1M1.78%Q4 202502
Solas Capital Management, LLC
CIK 0001604867
$11M1.9M6.08%Q1 202603
AWM Investment Company, Inc.
CIK 0001535264
$9M1.7M1.02%Q1 202604
Cable Car Capital, LP
CIK 0001699575
$8M1.4M2.62%Q1 202605
Ikarian Capital, LLC
CIK 0001778253
$6M1.1M0.47%Q1 202606
SPHERA FUNDS MANAGEMENT LTD.
CIK 0001496201
$3M568K0.49%Q1 202607
Alyeska Investment Group, L.P.
CIK 0001453072
$2M365K0.01%Q4 202508
BOOTHBAY FUND MANAGEMENT, LLC
CIK 0001549230
$1M256K0.02%Q1 202609
Aristides Capital LLC
CIK 0001595521
$1M219K0.26%Q1 202610
CANTOR FITZGERALD, L. P.
CIK 0001024896
$1M189K0.02%Q1 202611
CITADEL ADVISORS LLC
CIK 0001423053
$769,737118K0.00%Q4 202512
VILLERE ST DENIS J & CO LLC
CIK 0001113629
$390,65771K0.04%Q1 202613
MARSHALL WACE, LLP
CIK 0001318757
$345,82253K0.00%Q4 202514
TUDOR INVESTMENT CORP ET AL
CIK 0000923093
$338,16262K0.00%Q1 202615
ACT CAPITAL MANAGEMENT, LLC
CIK 0001442273
$282,73552K0.22%Q1 202616
TWO SIGMA INVESTMENTS, LP
CIK 0001179392
$87,21416K0.00%Q1 202617
Quadrature Capital Ltd
CIK 0001651424
$81,25713K0.00%Q4 202518
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$65,83612K0.00%Q1 202619
RAYMOND JAMES FINANCIAL INC
CIK 0000720005
$54,90010K0.00%Q1 202620
NATIONAL BANK OF CANADA /FI/
CIK 0000926171
$28,2985K0.00%Q1 2026
Page 1 of 2
8 more holders available. Log in →