AI Holders Summary · Q2 2026

29 institutions reported ACOG in Q2 2026. Opaleye Management Inc. leads at 26.1% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(1 on this page)

#HolderValueShares% port.Quarter

Opaleye Management Inc.

CIK 0001595855

$21M2.9M1.89%Q2 2026 02

Solas Capital Management, LLC

CIK 0001604867

$14M1.9M7.45%Q2 2026 03

AWM Investment Company, Inc.

CIK 0001535264

$12M1.7M1.05%Q2 2026 04

Cable Car Capital, LP

CIK 0001699575

$10M1.4M0.21%Q2 2026 05

Ikarian Capital, LLC

CIK 0001778253

$6M1.1M0.47%Q1 2026 06

SPHERA FUNDS MANAGEMENT LTD.

CIK 0001496201

$4M546K0.51%Q2 2026 07

ESSEX INVESTMENT MANAGEMENT CO LLC

CIK 0000201772

$4M423K0.56%Q3 2026 08

Alyeska Investment Group, L.P.

CIK 0001453072

$3M365K0.01%Q2 2026 09

Aristides Capital LLC

CIK 0001595521

$2M219K0.31%Q2 2026 10

CANTOR FITZGERALD, L. P.

CIK 0001024896

$2M218K0.01%Q2 2026 11

BOOTHBAY FUND MANAGEMENT, LLC

CIK 0001549230

$1M189K0.02%Q2 2026 12

CITADEL ADVISORS LLC

CIK 0001423053

$704K98K0.00%Q2 2026 13

VILLERE ST DENIS J & CO LLC

CIK 0001113629

$514K71K0.06%Q2 2026 14

ACT CAPITAL MANAGEMENT, LLC

CIK 0001442273

$372K52K0.24%Q2 2026 15

TUDOR INVESTMENT CORP ET AL

CIK 0000923093

$338K62K0.00%Q1 2026 16

BERKSHIRE ASSET MANAGEMENT LLC/PA

CIK 0000949012

$143K20K0.01%Q2 2026 17

TWO SIGMA INVESTMENTS, LP

CIK 0001179392

$136K19K0.00%Q2 2026 18

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$87K12K0.00%Q2 2026 19

RAYMOND JAMES FINANCIAL INC

CIK 0000720005

$72K10K0.00%Q2 2026 20

NATIONAL BANK OF CANADA /FI/

CIK 0000926171

$38K5K0.00%Q2 2026

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