AI Holders Summary · Q4 2025

58 institutions reported FBIO in Q4 2025. Opaleye Management Inc. leads at 24.9% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(5 on this page)

#HolderValueShares% port.Quarter

Opaleye Management Inc.

CIK 0001595855

$4M1.1M0.53%Q4 2025 02

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$3M966K0.00%Q1 2026 03

SUSQUEHANNA INTERNATIONAL GROUP, LLP

CIK 0001446194· Market maker

$1M507K0.00%Q1 2026 04

SHIKIAR ASSET MANAGEMENT INC

CIK 0001058022

$852K305K0.25%Q1 2026 05

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$810K290K0.00%Q1 2026 06

GSA CAPITAL PARTNERS LLP

CIK 0001362033

$709K254K0.04%Q1 2026 07

BlackRock, Inc.

CIK 0002012383

$688K225K0.00%Q2 2026 08

NORTHERN TRUST CORP

CIK 0000073124· Index

$642K230K0.00%Q1 2026 09

TWO SIGMA INVESTMENTS, LP

CIK 0001179392

$549K197K0.00%Q1 2026 10

BRIDGEWAY CAPITAL MANAGEMENT, LLC

CIK 0001107261

$509K182K0.01%Q1 2026 11

CITADEL ADVISORS LLC

CIK 0001423053

$417K114K0.00%Q4 2025 12

VANGUARD FIDUCIARY TRUST CO

CIK 0000933478· Index

$398K143K0.00%Q1 2026 13

HB Wealth Management, LLC

CIK 0001911253

$357K117K0.00%Q2 2026 14

Kestra Advisory Services, LLC

CIK 0001830819

$356K116K0.00%Q2 2026 15

STATE STREET CORP

CIK 0000093751

$311K102K0.00%Q2 2026 16

Sculptor Capital LP

CIK 0001054587

$290K104K0.00%Q1 2026 17

RENAISSANCE TECHNOLOGIES LLC

CIK 0001037389

$278K100K0.00%Q1 2026 18

Sheets Smith Investment Management

CIK 0001785199

$270K73K0.18%Q3 2025 19

WOLVERINE TRADING, LLC

CIK 0000927337

$253K65K0.00%Q3 2025 20

XTX Topco Ltd

CIK 0001828301

$212K76K0.00%Q1 2026

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