13F Insight
DOSSIER · 13F Holders · Q4 2025Inflation hedgeYield
FBIO

FORTRESS BIOTECH INC

58 institutions still hold FORTRESS BIOTECH INC as of Q4 2025. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 34960Q307·58 13F holders·last filed Dec 31, 2025
Market cap
—
▼ 7.8%
vs prior quarter
13F value held
$15M
68.0% inst. owned
of float
Holders
58
-50 QoQ
filers reporting
Activity
+22 / −86
+848 added · −757 reduced
this quarter
Concentration
27.30%
Opaleye Management Inc. #1
top holder share
AI Holders Summary · Q4 2025

58 institutions reported FBIO in Q4 2025. Opaleye Management Inc. leads at 27.3% of the visible book. -50 net institutions QoQ — distribution reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
Opaleye Management Inc.
CIK 0001595855
$4M1.1M0.53%Q4 202502
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$3M966K0.00%Q1 202603
SUSQUEHANNA INTERNATIONAL GROUP, LLP
CIK 0001446194· Market maker
$1M507K0.00%Q1 202604
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$810,110290K0.00%Q1 202605
NORTHERN TRUST CORP
CIK 0000073124· Index
$641,848230K0.00%Q1 202606
BlackRock, Inc.
CIK 0002012383
$549,867197K0.00%Q1 202607
TWO SIGMA INVESTMENTS, LP
CIK 0001179392
$549,142197K0.00%Q1 202608
BRIDGEWAY CAPITAL MANAGEMENT, LLC
CIK 0001107261
$508,807182K0.01%Q1 202609
CITADEL ADVISORS LLC
CIK 0001423053
$417,240114K0.00%Q4 202510
VANGUARD FIDUCIARY TRUST CO
CIK 0000933478· Index
$397,673143K0.00%Q1 202611
Kestra Advisory Services, LLC
CIK 0001830819
$362,145130K0.00%Q1 202612
HB Wealth Management, LLC
CIK 0001911253
$335,288120K0.00%Q1 202613
Sculptor Capital LP
CIK 0001054587
$290,160104K0.00%Q1 202614
STATE STREET CORP
CIK 0000093751
$283,467102K0.00%Q1 202615
RENAISSANCE TECHNOLOGIES LLC
CIK 0001037389
$277,856100K0.00%Q1 202616
Sheets Smith Investment Management
CIK 0001785199
$270,25973K0.18%Q3 202517
WOLVERINE TRADING, LLC
CIK 0000927337
$253,00065K0.00%Q3 202518
XTX Topco Ltd
CIK 0001828301
$212,23076K0.00%Q1 202619
Quadrature Capital Ltd
CIK 0001651424
$179,69149K0.00%Q4 202520
180 WEALTH ADVISORS, LLC
CIK 0001730817
$178,00264K0.02%Q1 2026
Page 1 of 3
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