AI Holders Summary · Q4 2025

169 institutions reported LRMR in Q4 2025. DEERFIELD MANAGEMENT COMPANY, L.P. leads at 39.8% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(2 on this page)

#HolderValueShares% port.Quarter

DEERFIELD MANAGEMENT COMPANY, L.P.

CIK 0001009258

$117M30.6M1.49%Q4 2025 02

Blue Owl Capital Holdings LP

CIK 0001858703

$32M7.1M8.61%Q1 2026 03

BlackRock, Inc.

CIK 0002012383

$17M3.8M0.00%Q1 2026 04

MILLENNIUM MANAGEMENT LLC

CIK 0001273087

$16M3.6M0.01%Q1 2026 05

AIGH Capital Management LLC

CIK 0001835943

$14M3.0M1.84%Q1 2026 06

DRIEHAUS CAPITAL MANAGEMENT LLC

CIK 0000938206

$13M2.9M0.10%Q1 2026 07

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$13M2.9M0.00%Q1 2026 08

DAFNA Capital Management LLC

CIK 0001389933

$9M2.0M2.08%Q1 2026 09

GOLDMAN SACHS GROUP INC

CIK 0000886982

$7M1.7M0.00%Q1 2026 10

RTW INVESTMENTS, LP

CIK 0001493215

$7M1.5M0.07%Q1 2026 11

Deep Track Capital, LP

CIK 0001856083

$7M1.5M0.11%Q1 2026 12

Woodline Partners LP

CIK 0001784547

$6M1.4M0.02%Q1 2026 13

CITADEL ADVISORS LLC

CIK 0001423053

$5M1.4M0.00%Q4 2025 14

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$5M1.1M0.00%Q1 2026 15

Soleus Capital Management, L.P.

CIK 0001802630

$5M1.1M0.19%Q1 2026 16

Point72 Asset Management, L.P.

CIK 0001603466

$5M1.0M0.01%Q1 2026 17

STATE STREET CORP

CIK 0000093751

$4M911K0.00%Q1 2026 18

Gem Investment Advisors, LLC

CIK 0001580018

$4M854K3.78%Q1 2026 19

Qube Research & Technologies Ltd

CIK 0001729829

$4M848K0.00%Q1 2026 20

AQR CAPITAL MANAGEMENT LLC

CIK 0001167557

$4M818K0.00%Q1 2026

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