DOSSIER · 13F Holders · Q1 2026High-convictionMulti-bagger
LYEL

LYELL IMMUNOPHARMA INC

78 institutions still hold LYELL IMMUNOPHARMA INC as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 55083r203·78 13F holders·last filed Mar 31, 2026
Market cap
6.6%
vs prior quarter
13F value held
$288M
74.0% inst. owned
of float
Holders
78
+91 QoQ
filers reporting
Activity
+40 / −85
+985 added · −834 reduced
this quarter
Concentration
22.62%
ARCH Venture Management, LLC #1
top holder share
AI Holders Summary · Q1 2026

78 institutions reported LYEL in Q1 2026. ARCH Venture Management, LLC leads at 22.6% of the visible book. +91 net new institutions vs prior quarter — accumulation reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
ARCH Venture Management, LLC
CIK 0001274403
$65M3.2M9.62%Q1 2026
02
MWG Caph Ltd
CIK 0002111120
$31M1.0M42.88%Q4 2025
03
GSK plc
CIK 0001131399
$30M1.5M5.06%Q1 2026
04
Foresite Capital Management IV, LLC
CIK 0001704132
$25M800K10.72%Q4 2025
05
Orland Properties Ltd
CIK 0001550093
$23M755K4.35%Q4 2025
06
MWG Management Ltd.
CIK 0001845151
$16M1.0M20.13%Q3 2025
07
Foresite Capital Management V, LLC
CIK 0001792206
$15M477K8.93%Q4 2025
08
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$14M718K0.00%Q1 2026
09
Almitas Capital LLC
CIK 0001596468
$12M578K2.62%Q1 2026
10
CITADEL ADVISORS LLC
CIK 0001423053
$10M341K0.00%Q4 2025
11
MILLENNIUM MANAGEMENT LLC
CIK 0001273087
$9M459K0.00%Q1 2026
12
venBio Partners LLC
CIK 0001776382
$7M338K2.41%Q1 2026
13
SUSQUEHANNA INTERNATIONAL GROUP, LLP
CIK 0001446194· Market maker
$6M310K0.00%Q1 2026
14
Alphabet Inc.
CIK 0001652044
$6M293K0.15%Q1 2026
15
HSG Holding Ltd
CIK 0001470766
$4M152K0.21%Q4 2025
16
BlackRock, Inc.
CIK 0002012383
$4M192K0.00%Q1 2026
17
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$3M167K0.00%Q1 2026
18
RENAISSANCE TECHNOLOGIES LLC
CIK 0001037389
$2M116K0.00%Q1 2026
19
GOLDMAN SACHS GROUP INC
CIK 0000886982
$2M114K0.00%Q1 2026
20
MARSHALL WACE, LLP
CIK 0001318757
$2M73K0.00%Q4 2025
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