AI Holders Summary · Q1 2026

78 institutions reported LYEL in Q1 2026. ARCH Venture Management, LLC leads at 22.6% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(3 on this page)

#HolderValueShares% port.Quarter

ARCH Venture Management, LLC

CIK 0001274403

$65M3.2M9.62%Q1 2026 02

MWG Caph Ltd

CIK 0002111120

$31M1.0M42.88%Q4 2025 03

GSK plc

CIK 0001131399

$30M1.5M5.06%Q1 2026 04

Foresite Capital Management IV, LLC

CIK 0001704132

$25M800K10.72%Q4 2025 05

Orland Properties Ltd

CIK 0001550093

$23M755K4.35%Q4 2025 06

MWG Management Ltd.

CIK 0001845151

$16M1.0M20.13%Q3 2025 07

Foresite Capital Management V, LLC

CIK 0001792206

$15M477K8.93%Q4 2025 08

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$14M718K0.00%Q1 2026 09

Almitas Capital LLC

CIK 0001596468

$12M578K2.62%Q1 2026 10

CITADEL ADVISORS LLC

CIK 0001423053

$10M341K0.00%Q4 2025 11

MILLENNIUM MANAGEMENT LLC

CIK 0001273087

$9M459K0.00%Q1 2026 12

venBio Partners LLC

CIK 0001776382

$7M338K2.41%Q1 2026 13

SUSQUEHANNA INTERNATIONAL GROUP, LLP

CIK 0001446194· Market maker

$6M310K0.00%Q1 2026 14

Alphabet Inc.

CIK 0001652044

$6M293K0.15%Q1 2026 15

HSG Holding Ltd

CIK 0001470766

$4M152K0.21%Q4 2025 16

BlackRock, Inc.

CIK 0002012383

$4M192K0.00%Q1 2026 17

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$3M167K0.00%Q1 2026 18

RENAISSANCE TECHNOLOGIES LLC

CIK 0001037389

$2M116K0.00%Q1 2026 19

GOLDMAN SACHS GROUP INC

CIK 0000886982

$2M114K0.00%Q1 2026 20

MARSHALL WACE, LLP

CIK 0001318757

$2M73K0.00%Q4 2025

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