13F Insight
DOSSIER · 13F Holders · Q1 2026Mega-capCrowded
MAZE

MAZE THERAPEUTICS INC

173 institutions still hold MAZE THERAPEUTICS INC as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 578784100·173 13F holders·last filed Mar 31, 2026
Market cap
—
▲ 0.8%
vs prior quarter
13F value held
$1.2B
47.0% inst. owned
of float
Holders
173
+120 QoQ
filers reporting
Activity
+24 / −87
+846 added · −757 reduced
this quarter
Concentration
11.14%
Frazier Life Sciences Management, L.P. #1
top holder share
AI Holders Summary · Q1 2026

173 institutions reported MAZE in Q1 2026. Frazier Life Sciences Management, L.P. leads at 11.1% of the visible book. +120 net new institutions vs prior quarter — accumulation reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
Frazier Life Sciences Management, L.P.
CIK 0001892134
$136M4.6M3.51%Q1 202602
TRV GP IV, LLC
CIK 0001688325
$134M4.5M50.04%Q1 202603
ARCH Venture Management, LLC
CIK 0001274403
$123M4.1M18.16%Q1 202604
Deep Track Capital, LP
CIK 0001856083
$104M3.5M1.70%Q1 202605
JANUS HENDERSON GROUP PLC
CIK 0001274173
$85M2.9M0.04%Q1 202606
Paradigm Biocapital Advisors LP
CIK 0001855655
$82M2.7M1.67%Q1 202607
BlackRock, Inc.
CIK 0002012383
$77M2.6M0.00%Q1 202608
VR Adviser, LLC
CIK 0001615982
$64M1.5M3.17%Q4 202509
a16z Capital Management, L.L.C.
CIK 0001540358
$51M1.7M3.94%Q1 202610
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$43M1.4M0.00%Q1 202611
Alphabet Inc.
CIK 0001652044
$41M1.4M1.03%Q1 202612
Logos Global Management LP
CIK 0001792126
$37M1.2M1.84%Q1 202613
Bellevue Group AG
CIK 0001674546
$37M888K0.70%Q4 202514
ADAGE CAPITAL PARTNERS GP, L.L.C.
CIK 0001165408
$35M1.2M0.05%Q1 202615
MARSHALL WACE, LLP
CIK 0001318757
$35M847K0.03%Q4 202516
ArrowMark Colorado Holdings LLC
CIK 0001483859
$32M767K0.70%Q4 202517
General Catalyst Group Management, LLC
CIK 0001637946
$31M1.0M16.85%Q1 202618
TRV GP V, LLC
CIK 0001990717
$28M951K7.08%Q1 202619
FMR LLC
CIK 0000315066
$26M864K0.00%Q1 202620
Casdin Capital, LLC
CIK 0001534261
$23M759K1.72%Q1 2026
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